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Terminated Phase 2 Interventional Results available

A Study of HBI-8000 (Tucidinostat) With Pembrolizumab in Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT05141357

Public ClinicalTrials.gov record NCT05141357. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination With Pembrolizumab for Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study identification

NCT ID
NCT05141357
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
HUYABIO International, LLC.
Industry
Enrollment
5 participants

Conditions and interventions

Interventions

  • HBI-8000 in combination with pembrolizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 14, 2022
Primary completion
Apr 18, 2023
Completion
Apr 18, 2023
Last update posted
Dec 23, 2025

2022 – 2023

United States locations

U.S. sites
7
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
Western Regional Medical Center Goodyear Arizona 85338
CBCC Global Research, Inc at Comprehensive Blood and Cancer Center Bakersfield California 93309
Hematology Oncology Associates Of The Treasure Coast Port Saint Lucie Florida 34952
Southeastern Regional Medical Center Newnan Georgia 30265
Midewestern Regional Medical Center, LLC Zion Illinois 60099
Cotton O'Neil Clinical Research Center Topeka Kansas 66606
Frederick Health-JMSCI Frederick Maryland 21702

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05141357, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 23, 2025 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05141357 live on ClinicalTrials.gov.

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