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Completed Phase 3 Interventional Results available

Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis

ClinicalTrials.gov ID: NCT05142774

Public ClinicalTrials.gov record NCT05142774. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 3:11 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Long-Term Extension Study to Evaluate the Safety and Efficacy of Tapinarof Cream, 1% in Subjects With Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an open-label, long-term multicenter, study to evaluate the safety and efficacy of topical tapinarof cream, 1% in subjects with atopic dermatitis. Subjects in this study have completed treatment in one of two Phase 3 pivotal studies (DMVT-505-3101 or DMVT-505-3102) or completed treatment in the DMVT-505-2104 study, or directly enrolled into this study. This study will consist of up to 48 weeks of treatment and a 1 week safety follow-up period.

Study identification

NCT ID
NCT05142774
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Organon and Co
Industry
Enrollment
728 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
2 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 28, 2021 (Actual)
Primary completion
Feb 29, 2024 (Actual)
Completion
Mar 7, 2024 (Actual)
Last update posted
Aug 13, 2025

2021 – 2024

United States locations

U.S. sites
102
U.S. states
29
U.S. cities
91
Facility City State ZIP Site status
Dermavant Investigative Site Birmingham Alabama 35244 —
Dermavant Investigative Site Phoenix Arizona 85032 —
Dermavant Investigative Site Scottsdale Arizona 85255 —
Dermavant Investigative Site Scottsdale Arizona 85260 —
Dermavant Investigative Site Bryant Arkansas 72022 —
Dermavant Investigative Site Fort Smith Arkansas 72916 —
Dermavant Investigative Site Cerritos California 90702 —
Dermavant Investigative Site Fountain Valley California 92708 —
Dermavant Investigative Site Fremont California 94538 —
Dermavant Investigative Site Huntington Beach California 92647 —
Dermavant Investigative Site Inglewood California 90301 —
Dermavant Investigative Site Lancaster California 93534 —
Dermavant Investigative Site Long Beach California 90806 —
Dermavant Investigative Site Los Angeles California 90017 —
Dermavant Investigative Site Los Angeles California 90033 —
Dermavant Investigative Site Los Angeles California 90045 —
Dermavant Investigative Site Mission Viejo California 92691 —
Dermavant Investigative Site Sacramento California 95815 —
Dermavant Investigative Site San Diego California 92123 —
Dermavant Investigative Site San Francisco California 94115 —
Dermavant Investigative Site Santa Ana California 92701 —
Dermavant Investigative Site Santa Monica California 90404 —
Dermavant Investigative Site Thousand Oaks California 91320 —
Dermavant Investigative Site Thornton Colorado 80112 —
Dermavant Investigative Site Washington D.C. District of Columbia 20037 —
Dermavant Investigative Site Boca Raton Florida 33428 —
Dermavant Investigative Site Boca Raton Florida 33486 —
Dermavant Investigative Site Brandon Florida 33511 —
Dermavant Investigative Site Coral Gables Florida 33146 —
Dermavant Investigative Site Delray Beach Florida 33484 —
Dermavant Investigative Site Hialeah Florida 33016 —
Dermavant Investigative Site Jacksonville Florida 32256 —
Dermavant Investigative Site Margate Florida 33063 —
Dermavant Investigative Site Miami Florida 33165 —
Dermavant Investigative Site Miami Florida 33173 —
Dermavant Investigative Site Miami Lakes Florida 33014 —
Dermavant Investigative Site Orlando Florida 32801 —
Dermavant Investigative Site Pinellas Park Florida 33781 —
Dermavant Investigative Site Sweetwater Florida 33172 —
Dermavant Investigative Site Tampa Florida 33607 —
Dermavant Investigative Site Marietta Georgia 30060 —
Dermavant Investigative Site Sandy Springs Georgia 30328 —
Dermavant Investigative Site Savannah Georgia 31406 —
Dermavant Investigative Site Snellville Georgia 30078 —
Dermavant Investigative Site Chicago Illinois 60611 —
Dermavant Investigative Site Evansville Indiana 47715 —
Dermavant Investigative Site Plainfield Indiana 46168 —
Dermavant Investigative Site Overland Park Kansas 66210 —
Dermavant Investigative Site Lexington Kentucky 40517 —
Dermavant Investigative Site Louisville Kentucky 40217 —
Dermavant Investigative Site Louisville Kentucky 40241 —
Dermavant Investigative Site Owensboro Kentucky 42301 —
Dermavant Investigative Site Baton Rouge Louisiana 70808 —
Dermavant Investigative Site Baton Rouge Louisiana 70809 —
Dermavant Investigative Site Covington Louisiana 70433 —
Dermavant Investigative Site Monroe Louisiana 71201 —
Dermavant Investigative Site New Orleans Louisiana 70115 —
Dermavant Investigative Site Largo Maryland 20774 —
Dermavant Investigative Site Rockville Maryland 20850 —
Dermavant Investigative Site Bay City Michigan 48706 —
Dermavant Investigative Site Clarkston Michigan 48346 —
Dermavant Investigative Site Warren Michigan 48088 —
Dermavant Investigative Site Ypsilanti Michigan 48197 —
Dermavant Investigative Site New Brighton Minnesota 55112 —
Dermavant Investigative Site Missoula Montana 59808 —
Dermavant Investigative Site Omaha Nebraska 68144 —
Dermavant Investigative Site East Windsor New Jersey 08520 —
Dermavant Investigative Site Garden City New York 11530 —
Dermavant Investigative Site New York New York 10075 —
Dermavant Investigative Site Charlotte North Carolina 28277 —
Dermavant Investigative Site Bexley Ohio 43209 —
Dermavant Investigative Site Cleveland Ohio 44106 —
Dermavant Investigative Site Dayton Ohio 45414 —
Dermavant Investigative Site Mason Ohio 45040 —
Dermavant Investigative Site Mayfield Heights Ohio 44124 —
Dermavant Investigative Site Norman Oklahoma 73071 —
Dermavant Investigative Site Oklahoma City Oklahoma 73120 —
Dermavant Investigative Site Tulsa Oklahoma 74114 —
Dermavant Investigative Site Medford Oregon 97504 —
Dermavant Investigative Site Portland Oregon 97210 —
Dermavant Investigative Site Portland Oregon 97223 —
Dermavant Investigative Site Portland Oregon 97239 —
Dermavant Investigative Site Anderson South Carolina 29621 —
Dermavant lnvestigative Site Greenville South Carolina 29615 —
Dermavant Investigative Site Mt. Pleasant South Carolina 29445 —
Dermavant Investigative Site North Charleston South Carolina 29420 —
Dermavant Investigative Site Spartanburg South Carolina 29303 —
Dermavant Investigative Site Knoxville Tennessee 37909 —
Dermavant Investigative Site Memphis Tennessee 38119 —
Dermavant Investigative Site Bellaire Texas 77401 —
Dermavant Investigative Site Cypress Texas 77433 —
Dermavant Investigative Site Dallas Texas 75230 —
Dermavant Investigative Site Dripping Springs Texas 78620 —
Dermavant Investigative Site Grapevine Texas 76051 —
Dermavant Investigative Site Houston Texas 77004 —
Dermavant Investigative Site San Antonio Texas 78213 —
Dermavant Investigative Site San Antonio Texas 78218 —
Dermavant Investigative Site San Antonio Texas 78229 —
Dermavant Investigative Site Sugar Land Texas 77479 —
Dermavant Investigative Site Webster Texas 77598 —
Dermavant Investigative Site Richmond Virginia 23226 —
Dermavant Investigative Site Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05142774, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 13, 2025 · Synced Oct 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05142774 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →