Extension Study of Infigratinib in Children With Achondroplasia (ACH)

ClinicalTrials.gov ID: NCT05145010

Public ClinicalTrials.gov record NCT05145010. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search

ClinicalTrials.gov public records Last synced Jul 22, 2026, 1:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2, Open-Label, Long-Term, Extension (OLE) Study of Infigratinib, an FGFR 1-3-Selective Tyrosine Kinase Inhibitor, in Children With Achondroplasia: PROPEL OLE

Study identification

NCT ID: NCT05145010
Recruitment status: Enrolling by invitation
Study type: Interventional
Phase: Phase 2
Lead sponsor: QED Therapeutics, a BridgeBio company; Industry
Enrollment: 300 participants

Conditions and interventions

Conditions

Achondroplasia

Interventions

Infigratinib Drug

Drug

Eligibility (public fields only)

Age range: 3 Years to 18 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 5, 2021
Primary completion: Nov 30, 2031
Completion: Jan 31, 2032
Last update posted: Oct 30, 2025

2021 – 2032

United States locations

U.S. sites: 8
U.S. states: 8
U.S. cities: 8

Facility	City	State	ZIP	Site status
USCF Benioff Children's Hospital, Oakland	Oakland	California	94609	—
Children's Hospital Colorado	Aurora	Colorado	80045	—
Nemours Alfred I. Dupont Hospital for Children	Wilmington	Delaware	19803	—
Johns Hopkins University	Baltimore	Maryland	21205	—
University of Missouri	Columbia	Missouri	65212	—
Cincinnati Children's Hospital Medical Center	Cincinnati	Ohio	45229	—
Vanderbilt University Medical Center	Nashville	Tennessee	37232	—
University Hospital and UW Health Clinics	Madison	Wisconsin	53705	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05145010, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 30, 2025 · Synced Jul 22, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05145010 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →