The CONFORM Pivotal Trial
Public ClinicalTrials.gov record NCT05147792. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Evaluation of the Safety and Effectiveness of the Conformal CLAAS System for Left Atrial Appendage Occlusion
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The CLAAS® device will be evaluated for safety and efficacy by establishing its performance is non-inferior to the commercially available WATCHMAN® and Amulet™ left atrial appendage closure devices in patients with non-valvular atrial fibrillation. Patients who are eligible for the trial will be randomized to receive either the CLAAS device or the WATCHMAN or Amulet™ devices and will be followed for 5 years after device implant.
Study identification
- NCT ID
- NCT05147792
- Recruitment status
- Suspended
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 1,600 participants
Conditions and interventions
Conditions
Interventions
- CLAAS Device
- WATCHMAN left atrial appendage closure device / Amulet left atrial appendage occluder Device
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 26, 2022 (Actual)
- Primary completion
- Jun 2028 (Estimated)
- Completion
- Dec 2031 (Estimated)
- Last update posted
- Sep 25, 2026
2022 – 2031
United States locations
- U.S. sites
- 79
- U.S. states
- 36
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Grandview Medical Center | Birmingham | Alabama | 35243 | — |
| Banner University Medical Center Phoenix | Phoenix | Arizona | 85006 | — |
| Abrazo Arizona Heart Hospital | Phoenix | Arizona | 85016 | — |
| Arizona Heart Arrhythmia Associates | Phoenix | Arizona | 85018 | — |
| HonorHealth | Scottsdale | Arizona | 85258 | — |
| Pima Heart & Vascular | Tucson | Arizona | 85719 | — |
| St. Bernard's Medical Center | Jonesboro | Arkansas | 72401 | — |
| Loma Linda University Health | Loma Linda | California | 92354 | — |
| Huntington Hospital | Pasadena | California | 91105 | — |
| Pacific Heart Institute | Santa Monica | California | 90405 | — |
| Community Memorial Hospital Ventura | Ventura | California | 93003 | — |
| South Denver Cardiology Associates | Littleton | Colorado | 80120 | — |
| Hartford Health Care St. Vincent's Medical Center | Bridgeport | Connecticut | 06606 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Ascension St. Vincent's Jacksonville | Jacksonville | Florida | 32204 | — |
| Largo Medical Center | Largo | Florida | 33770 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Baptist Health Care - Pensacola | Pensacola | Florida | 32503 | — |
| Sarasota Memorial Health Care System | Sarasota | Florida | 34239 | — |
| AdventHealth Tampa | Tampa | Florida | 33613 | — |
| USF - Tampa General Hospital | Tampa | Florida | 33620 | — |
| Piedmont Health Institute | Atlanta | Georgia | 30309 | — |
| Emory University | Atlanta | Georgia | 30342 | — |
| Northside Hospital, Inc | Atlanta | Georgia | 30342 | — |
| WellStar Kennestone Hospital | Marietta | Georgia | 30062 | — |
| Midwest Cardiovascular Institute | Naperville | Illinois | 60540 | — |
| Ascension St. Vincent - Carmel, IN | Indianapolis | Indiana | 46260 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| Terrebone - Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| Medstar Union Memorial Hospital | Baltimore | Maryland | 21218 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Lahey Hospital & Medical Centeer | Burlington | Massachusetts | 01805 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Henry Ford St. John Hospital | Detroit | Michigan | 48236 | — |
| Corewell Health | Grand Rapids | Michigan | 49503 | — |
| Henry Ford Providence Southfield Hospital | Southfield | Michigan | 48075 | — |
| M Health Fairview St. John's Hospital | Maplewood | Minnesota | 55109 | — |
| CentraCare Heart and Vascular Center | Saint Cloud | Minnesota | 56303 | — |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Kansas City Cardiac Arrhythmia Research, LLC | Overland | Missouri | 66211 | — |
| CHI Health / CommonSpirit Research Institute | Omaha | Nebraska | 68124 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Catholic Medical Center | Manchester | New Hampshire | 03102 | — |
| Deborah Heart and Lung | Browns Mills | New Jersey | 08015 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Cooper University - Heart House | Haddon Heights | New Jersey | 08104 | — |
| New Mexico Heart Institute | Albuquerque | New Mexico | 87102 | — |
| Albany Medical Center / Capital Cardiology Associates | Albany | New York | 12208 | — |
| University of Buffalo / Kaleida Health | Buffalo | New York | 14203 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Mission Hospital | Asheville | North Carolina | 28801 | — |
| TriHealth | Cincinnati | Ohio | 45242 | — |
| Ohio Health Research Institute | Columbus | Ohio | 43214 | — |
| ProMedica Toledo Hospital | Toledo | Ohio | 43606 | — |
| UPMC Harrisburg | Mechanicsburg | Pennsylvania | 17050 | — |
| Lankenau Heart Institute | Wynnewood | Pennsylvania | 19096 | — |
| Lifespan Health System | Providence | Rhode Island | 02903 | — |
| Prisma Health | Columbia | South Carolina | 29203 | — |
| HCA Grand Strand | Myrtle Beach | South Carolina | 29572 | — |
| Trident Medical Center | North Charleston | South Carolina | 29406 | — |
| Lexington Medical Center | West Columbia | South Carolina | 29169 | — |
| Erlanger Health System | Chattanooga | Tennessee | 37403 | — |
| Tennova Healthcare - Turkey Creek Medical Center | Knoxville | Tennessee | 37934 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| Memorial Hermann Memorial City Medical Center | Houston | Texas | 77094 | — |
| Baylor Scott & White Research Institute | Plano | Texas | 75093 | — |
| CHRISTUS Health | Tyler | Texas | 75701 | — |
| Sentara Norfolk | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219 | — |
| Chippenham Hospital | Richmond | Virginia | 23225 | — |
| Carilion Clinic | Roanoke | Virginia | 24014 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Bellin Health | Green Bay | Wisconsin | 54301 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05147792, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05147792 live on ClinicalTrials.gov.