ClinicalTrials.gov record
Evolut™ EXPAND TAVR II Pivotal Trial
ClinicalTrials.gov ID: NCT05149755
Public ClinicalTrials.gov record NCT05149755. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT05149755
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Enrollment
- 650 participants
Conditions and interventions
Conditions
Interventions
- Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT) Device
Device
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 26, 2022
- Primary completion
- Aug 31, 2027
- Completion
- Nov 30, 2034
- Last update posted
- May 18, 2026
2022 – 2034
United States locations
- U.S. sites
- 52
- U.S. states
- 30
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham (UAB) Hospital | Birmingham | Alabama | 35233 | — |
| Abrazo Arizone Heart Hospital | Phoenix | Arizona | 85016 | — |
| HonorHealth Scottsdale Shea Medical Center | Scottsdale | Arizona | 85260 | — |
| Los Robles Hospital & Medical Center | Thousand Oaks | California | 91360 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Saint Vincents Medical Center | Bridgeport | Connecticut | 06606-4201 | — |
| Hartford Hospital | Hartford | Connecticut | 06106 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| University of Florida | Gainesville | Florida | 32608 | — |
| Saint Vincent's Medical Center Riverside | Jacksonville | Florida | 32204 | — |
| Orlando Health | Orlando | Florida | 32806 | — |
| Tallahassee Memorial Hospital | Tallahassee | Florida | 32308-5054 | — |
| Tampa General Hospital | Tampa | Florida | 33620 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Terrebonne General Medical Center | Houma | Louisiana | 70360 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Michigan Health System - University Hospital | Ann Arbor | Michigan | 48109-1274 | — |
| Ascension Saint John Hospital | Detroit | Michigan | 48236 | — |
| Spectrum Health | Grand Rapids | Michigan | 49503 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| SSM Health Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| Catholic Medical Center | Manchester | New Hampshire | 03102 | — |
| Deborah Heart and Lung Center | Browns Mills | New Jersey | 08015 | — |
| Englewood Hospital & Medical Center | Englewood | New Jersey | 076931 | — |
| Northwell Health | Manhasset | New York | 11030 | — |
| The Mount Sinai Hospital | New York | New York | 10029 | — |
| Mission Hospital | Asheville | North Carolina | 28801 | — |
| Wake Forest University Heatlh Sciences | Winston-Salem | North Carolina | 27157 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106-1716 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Kettering Health Main Campus | Kettering | Ohio | 45429 | — |
| Oregon Health & Science University Hospital | Portland | Oregon | 97239 | — |
| Lehigh Valley Hospital, Inc | Allentown | Pennsylvania | 18103 | — |
| UPMC Pinnacle Harrisburg Campus | Harrisburg | Pennsylvania | 17101 | — |
| Monument Health Rapid City Hospital | Rapid City | South Dakota | 57701 | — |
| Erlanger Medical Center | Chattanooga | Tennessee | 37403 | — |
| Medical City Dallas | Dallas | Texas | 75230 | — |
| Texas Health Harris Methodist Hospital Fort Worth | Fort Worth | Texas | 76104 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Methodist Hospital San Antonio | San Antonio | Texas | 78229 | — |
| Intermountain Cardiovascular and Thoracic Surgery | Salt Lake City | Utah | 84111 | — |
| The University of Vermont | Burlington | Vermont | 05401-1473 | — |
| Carilion Roanoke Memorial Hospital | Roanoke | Virginia | 24014 | — |
| Providence Sacred Heart Medical Center & Children's Hospital | Spokane | Washington | 99204 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Aurora Saint Lukes Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 42 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05149755, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 18, 2026 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05149755 live on ClinicalTrials.gov.