EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial)
Public ClinicalTrials.gov record NCT05151172. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Prospective, Randomized, Parallel Group, Open-label Design to Determine the Efficacy and Safety of Endovascular Thrombectomy for Ischemic Stroke Patients With Symptomatic Acute Medium Vessel Intracranial Occlusions
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Stroke occurs when a blood clot causes a blockage in a blood vessel (artery) within the brain. This type of stroke is called an ischemic stroke and carries a high risk of disability or death. Stroke must be treated very fast. Any delay of even 10 minutes can result in the difference between an independent and a disabled outcome, and in some cases between life and death. Endovascular therapy (EVT) or Thrombectomy is a procedure to remove the blood clot (thrombus) from a blood vessel to reopen it (recanalization). Patients are likely to benefit from a thrombectomy procedure when it is performed in a larger blood vessel. Currently it is not known if thrombectomy procedure will benefit the patients presenting with the stroke that has been caused by a blood clot in a medium sized blood vessel (medium vessel occlusion, MeVO). This trial will enrol patients diagnosed with acute stroke due to a clot in the medium sized vessel. The patients will be randomized within 12 hours of their symptom onset to either standard of care or standard of care plus thrombectomy procedure. The participation will last for 12 months Escape MeVO coordinating centre is located at the University of Calgary. There will be up to 75 sites. We will be recruiting a total of 530 patients.
Study identification
- NCT ID
- NCT05151172
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 530 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 15, 2022 (Actual)
- Primary completion
- Dec 31, 2025 (Estimated)
- Completion
- Jun 30, 2026 (Estimated)
- Last update posted
- Aug 15, 2024
2022 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Baptist Health Medical Center | Little Rock | Arkansas | 72205-7299 | — |
| Sutter Health | San Francisco | California | 94109 | — |
| Providence Little company of Mary | Torrance | California | 90503 | — |
| Yale School of Medicine | New Haven | Connecticut | 06510 | — |
| Baptist Health Medical Centre | Jacksonville | Florida | 32207 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Northwestern Medicine | Chicago | Illinois | 60611 | — |
| Rush university Medical Centre | Chicago | Illinois | 60612 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| bBston Medican Center | Boston | Massachusetts | 02118 | — |
| Mount Sinai Health System | New York | New York | 10029 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Ohio Health (Columbus ORI) | Columbus | Ohio | 43214 | — |
| University of Toledo | Toledo | Ohio | 43606 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19017 | — |
| University of TN Health Sciences Centre | Memphis | Tennessee | 38163 | — |
| Texas stroke Institute | Plano | Texas | 75075 | — |
| Swedish Medical Centre | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05151172, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 15, 2024 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05151172 live on ClinicalTrials.gov.