A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular Edema
Public ClinicalTrials.gov record NCT05151731. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Double Masked, Active Comparator-Controlled Study to Investigate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7200220 Administered Intravitreally in Patients With Diabetic Macular Edema
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study BP43445 is a phase II, multicenter, randomized, double-masked, active comparator-controlled study to investigate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of vamikibart administered intravitreally in participants with diabetic macular edema. Only one eye will be chosen as the study eye. The duration of the study will be up to 76 weeks.
Study identification
- NCT ID
- NCT05151731
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 394 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2021 (Actual)
- Primary completion
- Nov 6, 2024 (Actual)
- Completion
- Apr 21, 2025 (Actual)
- Last update posted
- May 11, 2026
2021 – 2025
United States locations
- U.S. sites
- 36
- U.S. states
- 18
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Win Retina | Arcadia | California | 91006 | — |
| Retina Consultants, San Diego | Poway | California | 92064 | — |
| Retinal Consultants Med Group | Sacramento | California | 95825 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Colorado Retina Associates, PC | Lakewood | Colorado | 80228 | — |
| Emerson Clinical Research Institute LLC | Washington D.C. | District of Columbia | 20011-3010 | — |
| Rand Eye | Deerfield Beach | Florida | 33064 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Retina Institute | Orlando | Florida | 32806-1101 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33607 | — |
| Retina Specialists of Tampa | Wesley Chapel | Florida | 33544 | — |
| Butchertown Clinical Trials | Louisville | Kentucky | 40206 | — |
| Cumberland Valley Retina PC | Hagerstown | Maryland | 21740 | — |
| Deep Blue Retina PLLC | Southaven | Mississippi | 38671 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Opthalmic Consultants of LI | Lynbrook | New York | 11563 | — |
| University of Rochester Flaum Eye Institute | Rochester | New York | 14642 | — |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Meridian Clinical Research | Cincinnati | Ohio | 45219 | — |
| Verum Research LLC | Eugene | Oregon | 97401 | — |
| EyeHealth Northwest | Portland | Oregon | 97225 | — |
| Erie Retinal Surgery | Erie | Pennsylvania | 16507 | — |
| Eye Care Specialists, PC | Kingston | Pennsylvania | 18704 | — |
| Sewickley Eye Group | Sewickley | Pennsylvania | 15143 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Black Hills Eye Institute | Rapid City | South Dakota | 57701 | — |
| Retina Consultants of Nashville | Nashville | Tennessee | 37203 | — |
| Texas Retina Associates | Arlington | Texas | 75075 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| Valley Retina Institute P.A. | McAllen | Texas | 78503 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 78240 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Wagner Macula & Retina Center | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05151731, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05151731 live on ClinicalTrials.gov.