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Terminated Phase 3 Interventional

A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE

ClinicalTrials.gov ID: NCT05171049

Public ClinicalTrials.gov record NCT05171049. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 4:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Open-label, Blinded Endpoint Evaluation, Phase 3 Study Comparing the Effect of Abelacimab Relative to Apixaban on Venous Thromboembolism (VTE) Recurrence and Bleeding in Patients With Cancer Associated VTE

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 3,multicenter, randomized, open-label, blinded endpoint evaluation study comparing the effect of abelacimab relative to apixaban on venous thromboembolism (VTE) recurrence and bleeding in patients with cancer associated VTE (ASTER)

Study identification

NCT ID
NCT05171049
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Anthos Therapeutics, Inc.
Industry
Enrollment
1,150 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 5, 2022 (Actual)
Primary completion
Feb 4, 2026 (Actual)
Completion
Feb 4, 2026 (Actual)
Last update posted
Feb 23, 2026

2022 – 2026

United States locations

U.S. sites
23
U.S. states
17
U.S. cities
22
Facility City State ZIP Site status
University of Colorado Anschutz Medical Campus Aurora Colorado 80045 —
VA Connecticut Healthcare System West Haven Connecticut 06516-5907 —
Washington DC VAMC Washington D.C. District of Columbia 20422 —
University of Miami Health Miami Florida 33136 —
NorthShore University Health System Evanston Illinois 60201 —
University of Kentucky, Markey Cancer Center Lexington Kentucky 40536-0093 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215-5400 —
Henry Ford Health System Detroit Michigan 48202 —
Washington University St Louis Missouri 63110 —
Memorial Sloan Kettering Cancer Center-Middletown Middletown New Jersey 07748 —
Memorial Sloan Kettering Cancer Center-Commack Commack New York 11725 —
Memorial Sloan Kettering Cancer Center-West Harrison Harrison New York 10604 —
Memorial Sloan Kettering Cancer Center New York New York 10021-0005 —
Lipson Cancer Institute Rochester New York 14621 —
Duke University Medical Center Durham North Carolina 27710 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 —
University of Pennsylvania - Penn Blood Disorders Center Philadelphia Pennsylvania 19104 —
MD Anderson Cancer Center Houston Texas 77030 —
University of Texas Mays Cancer Center San Antonio Texas 78229 —
Gundersen Health System La Crosse Wisconsin 54601 —
Blood Center of Wisconsin Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 186 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05171049, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 23, 2026 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05171049 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →