Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia
Public ClinicalTrials.gov record NCT05182476. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Subjects With Cognitive Impairment Associated With Schizophrenia, Followed by Open-Label Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study to evaluate the safety and efficacy of luvadaxistat compared with placebo on improving cognitive performance in participants with schizophrenia.
Study identification
- NCT ID
- NCT05182476
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 216 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2021 (Actual)
- Primary completion
- Jun 28, 2024 (Actual)
- Completion
- Oct 14, 2024 (Actual)
- Last update posted
- Jul 2, 2025
2021 – 2024
United States locations
- U.S. sites
- 33
- U.S. states
- 11
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neurocrine Clinical Site | Phoenix | Arizona | 85012 | — |
| Neurocrine Clinical Site | Bentonville | Arkansas | 72712 | — |
| Neurocrine Clinical Site | Bryant | Arkansas | 72022 | — |
| Neurocrine Clinical Site | Anaheim | California | 92805 | — |
| Neurocrine Clinical Site | Bellflower | California | 90706 | — |
| Neurocrine Clinical Site | Garden Grove | California | 92845 | — |
| Neurocrine Clinical Site | Glendale | California | 91206 | — |
| Neurocrine Clinical Site | Oceanside | California | 92056 | — |
| Neurocrine Clinical Site | Pico Rivera | California | 90660 | — |
| Neurocrine Clinical Site | San Diego | California | 92102 | — |
| Neurocrine Clinical Site | San Diego | California | 92103 | — |
| Neurocrine Clinical Site | San Rafael | California | 94901 | — |
| Neurocrine Clinical Site | Stanford | California | 94305 | — |
| Neurocrine Clinical Site | Torrance | California | 90502 | — |
| Neurocrine Clinical Site | Aventura | Florida | 33180 | — |
| Neurocrine Clinical Site | Miami | Florida | 33016 | — |
| Neurocrine Clinical Site | Miami | Florida | 33133 | — |
| Neurocrine Clinical Site | Miami | Florida | 33144 | — |
| Neurocrine Clinical Site | Miami | Florida | 33176 | — |
| Neurocrine Clinical Site | Okeechobee | Florida | 34972 | — |
| Neurocrine Clinical Site | Pensacola | Florida | 32502 | — |
| Neurocrine Clinical Site | Tampa | Florida | 33629 | — |
| Neurocrine Clinical Site | Atlanta | Georgia | 30338 | — |
| Neurocrine Clinical Site | Chicago | Illinois | 60640 | — |
| Neurocrine Clinical Site | Ann Arbor | Michigan | 48105 | — |
| Neurocrine Clinical Site | Flowood | Mississippi | 39232 | — |
| Neurocrine Clinical Site | St Louis | Missouri | 63128 | — |
| Neurocrine Clinical Site | St Louis | Missouri | 63141 | — |
| Neurocrine Clinical Site | Cedarhurst | New York | 11516 | — |
| Neurocrine Clinical Site | New York | New York | 10032 | — |
| Neurocrine Clinical Site | New York | New York | 10035 | — |
| Neurocrine Clinical Site | DeSoto | Texas | 75115 | — |
| Neurocrine Clinical Site | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05182476, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2025 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05182476 live on ClinicalTrials.gov.