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Completed Phase 2 Interventional Results available

Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis

ClinicalTrials.gov ID: NCT05185089

Public ClinicalTrials.gov record NCT05185089. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 27, 2026, 2:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blind, Randomised, Placebo Controlled, Two Period Cross-Over Study to Evaluate the Efficacy and Safety of Orvepitant in Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis

Study identification

NCT ID
NCT05185089
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Nerre Therapeutics Ltd.
Industry
Enrollment
80 participants

Conditions and interventions

Interventions

  • Orvepitant Maleate Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2022
Primary completion
Jun 4, 2024
Completion
Jun 18, 2024
Last update posted
Nov 9, 2025

2022 – 2024

United States locations

U.S. sites
16
U.S. states
13
U.S. cities
16
Facility City State ZIP Site status
University of Southern California Los Angeles California 90033
University of California San Francisco California 94143
National Jewish Health Denver Colorado 80206
Loyola University Chicago Maywood Illinois 60153
Jadestone Clinical Research, LLC Silver Spring Maryland 20904
University of Michigan Ann Arbor Michigan 48109
Mayo Clinic Rochester Minnesota 55905
American Health Research Charlotte North Carolina 28277
PulmonIx, LLC Greensboro North Carolina 27403
Temple University Philadelphia Pennsylvania 19140
Medical University of South Carolina Charleston South Carolina 29424
Vanderbilt University Medical Center Nashville Tennessee 37204
Baylor University Dallas Texas 75246
Clear Lake Health Webster Texas 77598
University of Utah Salt Lake City Utah 84108
University of Virginia Health System Charlottesville Virginia 22908

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05185089, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 9, 2025 · Synced Jun 27, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05185089 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →