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Terminated Phase 2 Interventional Results available

A Phase 2b Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP)

ClinicalTrials.gov ID: NCT05194839

Public ClinicalTrials.gov record NCT05194839. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 5:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Dose Ranging Phase 2 Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects With Palmoplantar Pustulosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A 12-week Randomized, Double-blind, Placebo-controlled, Dose Ranging Phase 2 Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects with Palmoplantar Pustulosis followed by an Open-label Extension Phase.

Study identification

NCT ID
NCT05194839
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Aristea Therapeutics, Inc.
Industry
Enrollment
79 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 74 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 5, 2022 (Actual)
Primary completion
Feb 13, 2023 (Actual)
Completion
Mar 6, 2023 (Actual)
Last update posted
Jun 29, 2023

2022 – 2023

United States locations

U.S. sites
19
U.S. states
15
U.S. cities
19
Facility City State ZIP Site status
Total Skin & Beauty Dermatology Center, PC Birmingham Alabama 35205 —
Dermatology Trial Associates Bryant Arkansas 72022 —
Cosmetic Laser Dermatology San Diego California 92121 —
Clinical Science Institute Santa Monica California 90404 —
Driven Research LLC Coral Gables Florida 33134 —
Encore Medical Research, LLC Hollywood Florida 33021 —
Tory Sullivan, MD PA North Miami Beach Florida 33162 —
Advanced Medical Research PC Sandy Springs Georgia 30328 —
Dawes Fretzin Clinical Research Group, LLC Indianapolis Indiana 46250 —
DS Research Louisville Kentucky 40241 —
Great Lakes Research Group, Inc. Bay City Michigan 48706 —
Washington University School of Medicine-Dermatology St Louis Missouri 63108 —
Skin Specialists, PC (Schlessinger MD) Omaha Nebraska 68144 —
ALLCUTIS Research, LLC. Portsmouth New Hampshire 03801 —
Aventiv Research Inc. Dublin Ohio 43016 —
Apex Clinical Research Center Mayfield Heights Ohio 44124 —
Central Sooner Research Norman Oklahoma 73071 —
UPMC Department of Dermatology Pittsburgh Pennsylvania 15212 —
Dermatology Clinical Research Center of San Antonio San Antonio Texas 78229 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05194839, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 29, 2023 · Synced Oct 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05194839 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →