VIBRANT: VIB4920 for Active Lupus Nephritis
Public ClinicalTrials.gov record NCT05201469. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a Randomized Placebo-Controlled Double-Blind Multicenter Trial of VIB4920 for Active Lupus Nephritis (ITN091AI)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in participants with active lupus nephritis (LN).
Study identification
- NCT ID
- NCT05201469
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 74 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 15, 2022
- Primary completion
- Jul 31, 2026
- Completion
- Feb 28, 2027
- Last update posted
- Dec 18, 2025
2022 – 2027
United States locations
- U.S. sites
- 17
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California San Diego School of Medicine: Division of Rheumatology, Allergy and Immunology | La Jolla | California | 92093 | Recruiting |
| UCLA Medical Center: Division of Rheumatology | Los Angeles | California | 90095 | Recruiting |
| of California, Irvine School of Medicine Division of Rheumatology | Orange | California | 92868 | Recruiting |
| University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center | San Francisco | California | 94143 | Recruiting |
| University of Colorado School of Medicine: Division of Rheumatology | Aurora | Colorado | 80045 | Recruiting |
| Yale University School of Medicine: Section of Rheumatology | New Haven | Connecticut | 06519 | Recruiting |
| University of Miami Miller School of Medicine: Nephrology & Hypertension Division | Miami | Florida | 33136 | Recruiting |
| Emory University School of Medicine: Division of Rheumatology | Atlanta | Georgia | 30307 | Recruiting |
| University of Chicago, Department of Medicine: Rheumatology | Chicago | Illinois | 60637 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Washington University School of Medicine in St. Louis: Division of Nephrology | St Louis | Missouri | 63110 | Recruiting |
| Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases | Manhasset | New York | 11030 | Recruiting |
| Hospital for Special Surgery, New York: Division of Rheumatology | New York | New York | 10021 | Not yet recruiting |
| Columbia University Medical Center: Department of Medicine, Division of Rheumatology | New York | New York | 10032 | Recruiting |
| Penn State Health Milton S. Hershey Medical Center: Division of Rheumatology | Hershey | Pennsylvania | 17033 | Recruiting |
| Temple University, Lewis Katz School of Medicine, Department of Medicine: Nephrology | Philadelphia | Pennsylvania | 19140 | Recruiting |
| University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05201469, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 18, 2025 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05201469 live on ClinicalTrials.gov.