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Withdrawn Phase 1Phase 2 Interventional

A Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer.

ClinicalTrials.gov ID: NCT05205252

Public ClinicalTrials.gov record NCT05205252. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 10:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

ARIA: A Phase 1b/2, Open-label, Multi Cohort Trial of Tazemetostat in Combination With Various Treatments in Subjects With Relapsed or Refractory Hematologic Malignancies

Study identification

NCT ID
NCT05205252
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Epizyme, Inc.
Industry
Enrollment
Not listed

Conditions and interventions

Interventions

  • Tazemetostat Drug
  • Tafasitamab Drug
  • Lenalidomide Drug
  • Acalabrutinib Drug
  • Daratumumab (Intravenously) Drug
  • Mosunetuzumab Drug
  • Daratumumab (Subcutaneously) Drug
  • Hyaluronidase-Fihj Drug
  • Pomalidomide Drug
  • Dexamethasone 20mg Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 21, 2021
Primary completion
Jul 4, 2023
Completion
Jul 4, 2023
Last update posted
Aug 14, 2023

2021 – 2023

United States locations

U.S. sites
3
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
California Cancer Associates For Research And Excellence, cCARE Santa Fe California 92024
Central Care Cancer Center Bolivar Missouri 65613
Astera Cancer Center East Brunswick New Jersey 08816

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05205252, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 14, 2023 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05205252 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →