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Enrolling by invitation Phase 2 Interventional

Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD

ClinicalTrials.gov ID: NCT05210803

Public ClinicalTrials.gov record NCT05210803. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Long-term Follow-Up Study to Evaluate the Safety and Efficacy of Suprachoroidal Administration of RGX-314 for Participants With Neovascular Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a prospective study designed to evaluate the long-term safety and efficacy of ABBV-RGX-314. Eligible participants are those who were previously enrolled in a clinical study of nAMD in which they received suprachoroidal space (SCS) administration of ABBV-RGX-314. Enrollment of each participant in the current study should occur after the participant has completed either the end of study or early discontinuation visit in the previous (parent) clinical study. Participants will be followed for up to 5 years after ABBV-RGX-314 administration (inclusive of the parent study). As such, the total study duration for each participant may vary depending on when they enroll in the current study following ABBV-RGX-314 administration in the parent study.

Study identification

NCT ID
NCT05210803
Recruitment status
Enrolling by invitation
Study type
Interventional
Phase
Phase 2
Lead sponsor
AbbVie
Industry
Enrollment
116 participants

Conditions and interventions

Eligibility (public fields only)

Age range
Not listed
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 19, 2021
Primary completion
Jun 30, 2031
Completion
Jun 30, 2031
Last update posted
Aug 4, 2026

2021 – 2031

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
16
Facility City State ZIP Site status
Retinal Research Institute, LLC Phoenix Arizona 85014
California Retina Consultants Bakersfield California 93309
Retina-Vitreous Associates Medical Group Beverly Hills California 90211
Northern California Retina Vitreous Associates Medical Group Inc Mountain View California 94040
Retina Consultants San Diego Poway California 92064
California Retina Consultants Santa Barbara California 93103
Southeast Retina Center PC Augusta Georgia 30909
Johns Hopkins University Baltimore Maryland 21205
Ophthalmic Consultants of Boston Boston Massachusetts 02114
Vitreoretinal Surgery PLLC Edina Minnesota 55435
Sierra eye Associates Reno Nevada 89502
Vision Research Center Eye Associates of New Mexico Albuquerque New Mexico 87109
Retinovitreous Associates, LTD Philadelphia Pennsylvania 19107
Charles Retina Institute, P.C Germantown Tennessee 38138
Tennessee Retina, PC Nashville Tennessee 37203
Retina Consultants of Texas The Woodlands Texas 77384

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05210803, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 4, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05210803 live on ClinicalTrials.gov.

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