Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic Modeling

ClinicalTrials.gov ID: NCT05219604

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Official title

The Magnitude and Duration of the Central Nervous System Effects Following Intravenous Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic Modeling

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study seeks to explore the magnitude and duration of central nervous system effects and pharmacokinetics after intravenous infusion of diphenhydramine.

Study identification

NCT ID: NCT05219604
Recruitment status: Terminated
Study type: Interventional
Phase: Phase 4
Lead sponsor: Dent Neuroscience Research Center; Other
Enrollment: 3 participants

Conditions and interventions

Conditions

Interventions

DiphenhydrAMINE Injectable Solution Drug

Drug

Eligibility (public fields only)

Age range: 35 Years and older
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 15, 2022 (Actual)
Primary completion: Oct 4, 2022 (Actual)
Completion: Oct 4, 2022 (Actual)
Last update posted: Jan 22, 2026

2022

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
Dent Neurologic Institute	Amherst	New York	14226	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05219604, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 22, 2026 · Synced Nov 15, 2026