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Completed Phase 1 Interventional Results available

Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis

ClinicalTrials.gov ID: NCT05225805

Public ClinicalTrials.gov record NCT05225805. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 1:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-Label, Randomized, Crossover Study to Assess the Safety and Pharmacokinetics Following Single Doses of Oral and Intravenous Xenleta (Lefamulin) in Adult Patients With Cystic Fibrosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is intended to assess the pharmacokinetic (PK) and safety of a single dose of IV and oral formulations of lefamulin in adults with cystic fibrosis (CF).

Study identification

NCT ID
NCT05225805
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Nabriva Therapeutics AG
Industry
Enrollment
13 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2022
Primary completion
Sep 19, 2022
Completion
Jan 12, 2023
Last update posted
Jun 16, 2024

2022 – 2023

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
University of Kansas School of Medicine Kansas City Kansas 66160
Boston Children's Hospital Boston Massachusetts 02115
New York Medical College Valhalla New York 10595
University Hospitals Cleveland Medical Center Cleveland Ohio 44106
Penn State University College of Medicine Hershey Pennsylvania 17033
University of Utah Salt Lake City Utah 84112

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05225805, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 16, 2024 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05225805 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →