Elpipodect (MK-8189) Safety and Tolerability in Participants With Alzheimer's Disease With or Without Symptoms of Agitation-Aggression and/or Psychosis (MK-8189-017)
Public ClinicalTrials.gov record NCT05227118. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Clinical Study to Evaluate the Safety and Tolerability of MK-8189 in Participants With Alzheimer's Disease With or Without Symptoms of Agitation-Aggression and/or Psychosis
Study identification
- NCT ID
- NCT05227118
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 29 participants
Conditions and interventions
Conditions
Interventions
- Elpipodect Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 65 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2022
- Primary completion
- Jan 9, 2023
- Completion
- Jan 9, 2023
- Last update posted
- Apr 28, 2026
2022 – 2023
United States locations
- U.S. sites
- 8
- U.S. states
- 5
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CITrials ( Site 0007) | Santa Ana | California | 92705 | — |
| Top Medical Research ( Site 0005) | Cutler Bay | Florida | 33189 | — |
| Velocity Clinical Research, Hallandale Beach ( Site 0001) | Hallandale | Florida | 33009 | — |
| Well Pharma Medical Research, Corp. ( Site 0006) | Miami | Florida | 33173 | — |
| Atlanta Center for Medical Research ( Site 0004) | Atlanta | Georgia | 30331 | — |
| iResearch Atlanta ( Site 0009) | Decatur | Georgia | 30030 | — |
| Global Medical Institutes LLC; Princeton Medical Institute ( Site 0008) | Princeton | New Jersey | 08540 | — |
| Richmond Behavioral Associates ( Site 0003) | Staten Island | New York | 10314 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05227118, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 28, 2026 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05227118 live on ClinicalTrials.gov.