A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration
Public ClinicalTrials.gov record NCT05230537. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Participant and Investigator Masked, Placebo-controlled, Multicenter, Proof-of-concept Study to Assess the Safety and Efficacy of LNP023 (Iptacopan) in Patients With Early and Intermediate Age-related Macular Degeneration
Study identification
- NCT ID
- NCT05230537
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 170 participants
Conditions and interventions
Conditions
Interventions
- Iptacopan (LNP023) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 16, 2022
- Primary completion
- Sep 30, 2026
- Completion
- Oct 1, 2026
- Last update posted
- Jul 2, 2025
2022 – 2026
United States locations
- U.S. sites
- 22
- U.S. states
- 12
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Salehi Retina Institute | Huntington Beach | California | 92647 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95841 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| Southwest Retina Research Center | Durango | Colorado | 81303 | — |
| Advanced Research LLC | Deerfield Beach | Florida | 33064 | — |
| Retina Center Of South Florida | Delray Beach | Florida | 33484 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46280 | — |
| Retina Associates New Orleans | New Orleans | Louisiana | 70115 8139 | — |
| Retina Care Center | Baltimore | Maryland | 21209 | — |
| Opthamalic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Envision Ocular LLC | Bloomfield | New Jersey | 07003 | — |
| Duke Eye Center | Durham | North Carolina | 27705 | — |
| Retina Northwest PC | Portland | Oregon | 97210 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Austin Research Center for Retina | Austin | Texas | 78793 | — |
| Retina Consultants TX Rsrch Ctr | Bellaire | Texas | 77401 | — |
| Retina Foundation | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Fort Worth | Texas | 76104 | — |
| Retina Consultants of Houston PA | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05230537, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05230537 live on ClinicalTrials.gov.