Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Terminated Phase 2 Interventional Results available

Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)

ClinicalTrials.gov ID: NCT05237284

Public ClinicalTrials.gov record NCT05237284. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 7:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of SAR443820 in Adult Participants With Amyotrophic Lateral Sclerosis, Followed by an Open-label Extension

Study identification

NCT ID
NCT05237284
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sanofi
Industry
Enrollment
305 participants

Conditions and interventions

Interventions

  • SAR443820 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 12, 2022
Primary completion
Mar 6, 2024
Completion
Mar 6, 2024
Last update posted
Mar 20, 2025

2022 – 2024

United States locations

U.S. sites
17
U.S. states
11
U.S. cities
16
Facility City State ZIP Site status
UC San Diego Health Site Number : 8400022 La Jolla California 92121
USC Site Number : 8400008 Los Angeles California 90033
University of California Irvine Site Number : 8400012 Orange California 92868
California Pacific Medical Center Site Number : 8400015 San Francisco California 94115
University of Colorado Site Number : 8400025 Aurora Colorado 80045
Georgetown University Medical Center Site Number : 8400020 Washington D.C. District of Columbia 20007
Mayo Clinic Site Number : 8400029 Jacksonville Florida 32224
AdventHealth Medical Group - Neurology at Winter Park Site Number : 8400006 Winter Park Florida 32789
Northwestern Medical Group, Department of Neurology Site Number : 8400003 Chicago Illinois 60611
Johns Hopkins University Site Number : 8400028 Baltimore Maryland 21287
Massachusetts General Hospital Site Number : 8400001 Boston Massachusetts 02114
Mount Sinai - Union Square Site Number : 8400002 New York New York 10003
Penn State Milton S. Hershey Medical Center Site Number : 8400004 Hershey Pennsylvania 17033
University of Pennsylvania Site Number : 8400021 Philadelphia Pennsylvania 19104
Thomas Jefferson University Hospital Site Number : 8400014 Philadelphia Pennsylvania 19107
University of Utah Site Number : 8400009 Salt Lake City Utah 84132
Froedtert Hospital & Medical College of Wisconsin Site Number : 8400010 Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05237284, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 20, 2025 · Synced Jul 23, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05237284 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →