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Completed Phase 2 Interventional

A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease

ClinicalTrials.gov ID: NCT05238597

Public ClinicalTrials.gov record NCT05238597. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 1:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Double-Masked, Randomized, Vehicle-Controlled Clinical Trial Evaluating the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The objectives of this trial are to assess the safety, tolerability and efficacy of A197 ophthalmic solution in comparison to a vehicle control in the treatment of subjects with Dry Eye Disease.

Study identification

NCT ID
NCT05238597
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Aramis Biosciences, Inc.
Industry
Enrollment
207 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 24, 2022
Primary completion
Jan 23, 2023
Completion
Jan 23, 2023
Last update posted
May 15, 2023

2022 – 2023

United States locations

U.S. sites
24
U.S. states
11
U.S. cities
24
Facility City State ZIP Site status
Aramis Site 113 Birmingham Alabama 35233
Aramis Site 121 Garden Grove California 92843
Aramis Site 120 Glendale California 95817
Aramis Site 106 Long Beach California 90805
Aramis Site 124 Los Angeles California 90013
Aramis Site 107 Murrieta California 92562
Aramis Site 102 Newport Beach California 92663
Aramis Site 116 Petaluma California 94954
Aramis Site 109 Rancho Cordova California 95670
Aramis Site 101 Delray Beach Florida 33484
Aramis Site 112 Jacksonville Florida 32204
Aramis Site 117 Largo Florida 33773
Aramis Site 118 Edgewood Kentucky 41017
Aramis Site 114 Kansas City Missouri 64111
Aramis Site 111 St Louis Missouri 63128
Aramis Site 108 Las Vegas Nevada 89119
Aramis Site 110 Garner North Carolina 27529
Aramis Site 122 Shelby North Carolina 28150
Aramis Site 119 Mason Ohio 45040
Aramis Site 123 Cranberry Township Pennsylvania 16066
Aramis Site 115 Goodlettsville Tennessee 37072
Aramis Site 103 Memphis Tennessee 38119
Aramis Site 104 Lakeway Texas 78738
Aramis Site 105 San Antonio Texas 78215

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05238597, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 15, 2023 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05238597 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →