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Completed Phase 2 Interventional

A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis

ClinicalTrials.gov ID: NCT05238675

Public ClinicalTrials.gov record NCT05238675. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Double-blind, Placebo-controlled, Parallel Group, Dose-finding Study Evaluating Efficacy, Safety and Tolerability of BI 1291583 qd Over at Least 24 Weeks in Patients With Bronchiectasis (AirleafTM)

Study identification

NCT ID
NCT05238675
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
322 participants

Conditions and interventions

Conditions

Interventions

  • BI 1291583 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 27, 2022
Primary completion
Apr 30, 2024
Completion
May 29, 2024
Last update posted
Aug 13, 2025

2022 – 2024

United States locations

U.S. sites
16
U.S. states
9
U.S. cities
15
Facility City State ZIP Site status
Phoenix Medical Group Peoria Arizona 85381
Newport Native MD, Inc Newport Beach California 92663
University of California Davis Sacramento California 95817
Central Florida Pulmonary Group Altamonte Springs Florida 32701
Malcom Randall VA Medical Center Gainesville Florida 32608
University of Florida College of Medicine Jacksonville Florida 32209
University of Kansas Medical Center Kansas City Kansas 66160
New York University Langone Medical Center New York New York 10016
NewYork-Presbyterian/Weill Cornell Medical Center New York New York 10065
Southeastern Research Center Winston-Salem North Carolina 27103
University of Cincinnati Cincinnati Ohio 45267
Medical University of South Carolina Charleston South Carolina 29425
Institute for Translational Oncology Research Greenville South Carolina 29605
Metroplex Pulmonary & Sleep Center McKinney Texas 75069
Diagnostics Research Group San Antonio Texas 78229
University of Texas Health Science Center at Tyler Tyler Texas 75708

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 96 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05238675, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 13, 2025 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05238675 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →