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Completed Phase 2 Interventional Results available

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

ClinicalTrials.gov ID: NCT05239468

Public ClinicalTrials.gov record NCT05239468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a, Double-Blind, Randomized, Active Controlled, Parallel Group Study Evaluating the Efficacy, Safety, and Tolerability of Bezafibrate Administered in Combination With Obeticholic Acid in Subjects With Primary Biliary Cholangitis

Study identification

NCT ID
NCT05239468
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Intercept Pharmaceuticals
Industry
Enrollment
72 participants

Conditions and interventions

Interventions

  • Bezafibrate 100 mg Drug
  • Bezafibrate 200 mg Drug
  • Obeticholic Acid 5 mg Drug
  • Obeticholic Acid placebo Drug
  • Bezafibrate Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 20, 2022
Primary completion
Aug 31, 2025
Completion
Aug 31, 2025
Last update posted
Jul 15, 2026

2022 – 2025

United States locations

U.S. sites
17
U.S. states
12
U.S. cities
17
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233
Southern California Gastrointestinal (GI) and Liver Centers (SCLC) - Coronado Coronado California 92118
Facey Medical Group Mission Hills California 91345
Schiff Center for Liver Diseases / University of Miami Miami Florida 33136
Tampa General Medical Group Tampa Florida 33606
Piedmont Atlanta Hospital Atlanta Georgia 30309
Loyola University Medical Center Maywood Illinois 60459
Ochsner Medical Center New Orleans Louisiana 70121
Beth Israel Deaconess Medical Center Harvard Liver Research Center Boston Massachusetts 02215
NYU Langone Medical Center New York New York 10016-6402
Wake Endoscopy Center Raleigh North Carolina 27607
University Hospitals Cleveland Medical Center Cleveland Ohio 44106
Gastro One Cordova Tennessee 38018
Gastrointestinal Associates of Northeast Tennessee Johnson City Tennessee 37604
Methodist Clinical Research Institute (CRI) Dallas Texas 75203
Houston Methodist Cancer Center Houston Texas 77030-2717
American Research Corporation at the Texas Liver Institute San Antonio Texas 78215

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05239468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 15, 2026 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05239468 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →