Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC
Public ClinicalTrials.gov record NCT05239468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Double-Blind, Randomized, Active Controlled, Parallel Group Study Evaluating the Efficacy, Safety, and Tolerability of Bezafibrate Administered in Combination With Obeticholic Acid in Subjects With Primary Biliary Cholangitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study to determine the effect of the investigational drug bezafibrate (BZF) alone and in combination with the investigational drug obeticholic acid (OCA) in participants with Primary Biliary Cholangitis (PBC).
Study identification
- NCT ID
- NCT05239468
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 72 participants
Conditions and interventions
Conditions
Interventions
- Bezafibrate 100 mg Drug
- Bezafibrate 200 mg Drug
- Obeticholic Acid 5 mg Drug
- Obeticholic Acid placebo Drug
- Bezafibrate Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 21, 2022 (Actual)
- Primary completion
- Sep 1, 2025 (Actual)
- Completion
- Sep 1, 2025 (Actual)
- Last update posted
- Jul 16, 2026
2022 – 2025
United States locations
- U.S. sites
- 17
- U.S. states
- 12
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Southern California Gastrointestinal (GI) and Liver Centers (SCLC) - Coronado | Coronado | California | 92118 | — |
| Facey Medical Group | Mission Hills | California | 91345 | — |
| Schiff Center for Liver Diseases / University of Miami | Miami | Florida | 33136 | — |
| Tampa General Medical Group | Tampa | Florida | 33606 | — |
| Piedmont Atlanta Hospital | Atlanta | Georgia | 30309 | — |
| Loyola University Medical Center | Maywood | Illinois | 60459 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Beth Israel Deaconess Medical Center Harvard Liver Research Center | Boston | Massachusetts | 02215 | — |
| NYU Langone Medical Center | New York | New York | 10016-6402 | — |
| Wake Endoscopy Center | Raleigh | North Carolina | 27607 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Gastro One | Cordova | Tennessee | 38018 | — |
| Gastrointestinal Associates of Northeast Tennessee | Johnson City | Tennessee | 37604 | — |
| Methodist Clinical Research Institute (CRI) | Dallas | Texas | 75203 | — |
| Houston Methodist Cancer Center | Houston | Texas | 77030-2717 | — |
| American Research Corporation at the Texas Liver Institute | San Antonio | Texas | 78215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05239468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 16, 2026 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05239468 live on ClinicalTrials.gov.