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Active, not recruiting Phase 2 Interventional

Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer

ClinicalTrials.gov ID: NCT05239533

Public ClinicalTrials.gov record NCT05239533. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 5:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Open-label Study of Nivolumab Combined With Lutetium 177-Labeled Anti-Carbonic Anhydrase IX Monoclonal Antibody Girentuximab in Patients With Clear Cell Advanced Renal Cell Carcinoma

Study identification

NCT ID
NCT05239533
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Enrollment
9 participants

Conditions and interventions

Interventions

  • 177Lu-labeled-girentuximab Drug
  • Nivolumab Drug
  • 89Zr-girentuximab PET/CT Diagnostic Test
  • 177Lu whole body (WB) planar and SPECT/CT scans Diagnostic Test

Drug · Diagnostic Test

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 15, 2022
Primary completion
Feb 28, 2027
Completion
Feb 28, 2027
Last update posted
Jan 13, 2026

2022 – 2027

United States locations

U.S. sites
7
U.S. states
2
U.S. cities
7
Facility City State ZIP Site status
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) Basking Ridge New Jersey 07920
Memorial Sloan Kettering Monmouth (Limited Protocol Activities) Middletown New Jersey 07748
Memorial Sloan Kettering Bergen (Limited Protocol Activities) Montvale New Jersey 07645
Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities) Commack New York 11725
Memorial Sloan Kettering Westchester (Limited Protocol Activites) Harrison New York 10604
Memorial Sloan Kettering Cancer Center (All Protocol Activities) New York New York 10065
Memorial Sloan Kettering Nassau (Limited Protocol Activites) Uniondale New York 11553

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05239533, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 13, 2026 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05239533 live on ClinicalTrials.gov.

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