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Not listed Not applicable Interventional

NGS vs Culture Outcomes for Treatment of PJI

ClinicalTrials.gov ID: NCT05247281

Public ClinicalTrials.gov record NCT05247281. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized Controlled Trial Investigating the Use of Next-generation Sequencing in Directing the Antimicrobial Treatment of Periprosthetic Joint Infection

Study identification

NCT ID
NCT05247281
Recruitment status
Not listed
Study type
Interventional
Phase
Not applicable
Lead sponsor
Center for Innovation and Research Organization
Network
Enrollment
250 participants

Conditions and interventions

Interventions

  • Culture-based treatment Diagnostic Test
  • Next Generation Sequencing (NGS) with Culture Diagnostic Test

Diagnostic Test

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 20, 2022
Primary completion
Apr 30, 2024
Completion
Apr 30, 2025
Last update posted
Nov 7, 2023

2022 – 2025

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
University of Southern California Los Angeles California 90033
Cleveland Clinic Florida Weston Florida 33331
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03766
Columbia University New York New York 10032
University of Rochester Rochester New York 14618
Northwell Health Staten Island New York 10309
Cleveland Clinic Ohio Cleveland Ohio 44195
Rothman Orthopaedic Institute Philadelphia Pennsylvania 19107
University of Utah Salt Lake City Utah 84108

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05247281, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 7, 2023 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05247281 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →