4D-710 in Adult Patients With Cystic Fibrosis

ClinicalTrials.gov ID: NCT05248230

Public ClinicalTrials.gov record NCT05248230. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 3, 2026, 4:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Phase 1/2 Trial of Gene Therapy 4D-710 in Adults With Cystic Fibrosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis.

Study identification

NCT ID: NCT05248230
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: 4D Molecular Therapeutics; Industry
Enrollment: 30 participants

Conditions and interventions

Conditions

Cystic Fibrosis Lung

Interventions

4D-710 Biological

Biological

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 28, 2022
Primary completion: May 31, 2027
Completion: May 31, 2031
Last update posted: Jul 5, 2026

2022 – 2031

United States locations

U.S. sites: 20
U.S. states: 16
U.S. cities: 19

Facility	City	State	ZIP	Site status
University of Alabama Child Health Research Unit	Birmingham	Alabama	35233	Recruiting
The University of Arizona	Tucson	Arizona	85724	Recruiting
University of California San Francisco	San Francisco	California	94143	Recruiting
National Jewish Health	Denver	Colorado	80206	Recruiting
University of Florida	Gainesville	Florida	32610	Recruiting
University of Miami Hospital	Miami	Florida	33136	Recruiting
Northwestern Memorial Hospital	Chicago	Illinois	60611	Recruiting
University of Kansas Medical Center	Kansas City	Kansas	66160	Recruiting
Johns Hopkins Hospital	Baltimore	Maryland	21287	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Boston Children's Hospital	Boston	Massachusetts	02115	Recruiting
University of North Carolina at Chapel Hill	Chapel Hill	North Carolina	27599	Completed
Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center	Cleveland	Ohio	44146	Recruiting
Nationwide Children's Hospital	Columbus	Ohio	43205	Recruiting
Penn State Health	Hershey	Pennsylvania	17033	Withdrawn
The Hospital of the University of Pennsylvania	Philadelphia	Pennsylvania	19104	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Recruiting
The University of Texas Southwestern Medical Center	Dallas	Texas	75390	Recruiting
Virginia Commonwealth University Health System	Richmond	Virginia	23298	Recruiting
University of Washington Medical Center	Seattle	Washington	98195	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05248230, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 5, 2026 · Synced Sep 3, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05248230 live on ClinicalTrials.gov.

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