ClinicalTrials.gov record
Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)
ClinicalTrials.gov ID: NCT05248646
Public ClinicalTrials.gov record NCT05248646. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects With Immunoglobulin A Nephropathy.
Study identification
- NCT ID
- NCT05248646
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Industry
- Enrollment
- 530 participants
Conditions and interventions
Conditions
Interventions
- Sibeprenlimab 400 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 14, 2022
- Primary completion
- May 12, 2026
- Completion
- Jan 18, 2027
- Last update posted
- Jul 13, 2026
2022 – 2027
United States locations
- U.S. sites
- 54
- U.S. states
- 23
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham - Site #336 | Birmingham | Alabama | 35233 | — |
| Mayo Clinic Arizona - Site #363 | Phoenix | Arizona | 85054 | — |
| University of Arkansas for Medical Sciences - Site #353 | Little Rock | Arkansas | 72205 | — |
| Amicis Research Center - Site #341 | Granada Hills | California | 91344 | — |
| University of CA San Diego - Site #351 | La Jolla | California | 92037 | — |
| California Institute of Renal Research - Site #371 | La Mesa | California | 91942 | — |
| Loma Linda University Health Care Clinical Trial Center Clinic - Site #372 | Loma Linda | California | 92354 | — |
| Academic Medical Research Institute - Site #333 | Los Angeles | California | 90022 | — |
| Kaiser Permanente - Southern California Permanente Medical Group SCPMG - LAMC - Site #325 | Los Angeles | California | 90027 | — |
| Stanford University - Site #370 | Palo Alto | California | 94304 | — |
| North America Research Institute - Site #335 | San Dimas | California | 91773 | — |
| University of California, San Francisco - Site #377 | San Francisco | California | 94143 | — |
| Colorado Kidney Care PC - Site #330 | Denver | Colorado | 80230 | — |
| Mayo Clinic in Florida - Site #321 | Jacksonville | Florida | 32224 | — |
| South Florida Research Institute - Site #323 | Lauderdale Lakes | Florida | 33313 | — |
| Columbus Research Group - Site #376 | South Miami | Florida | 33143 | — |
| Fides Clinical Research North Atlanta Kidney Specialists - Site #373 | Atlanta | Georgia | 30342 | — |
| Georgia Nephrology - Site #356 | Lawrenceville | Georgia | 30046 | — |
| University of Iowa Hospitals & Clinics - Site #359 | Iowa City | Iowa | 52242 | — |
| Kansas Nephrology Associates - Site #322 | Wichita | Kansas | 67214 | — |
| Ochsner Medical Center - Site #334 | New Orleans | Louisiana | 70121 | — |
| University of Maryland - Site #355 | Baltimore | Maryland | 21201 | — |
| MGH Harvard - Site #369 | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital, Division of Renal Medicine - Site #379 | Boston | Massachusetts | 02115 | — |
| Tufts Medical Center - Site #349 | Boston | Massachusetts | 02127 | — |
| Beth Israel Deaconess Medical Center - Site #337 | Boston | Massachusetts | 02215 | — |
| MGH Harvard - Site #369 | Boston | Massachusetts | 21144 | — |
| Brigham and Women's Hospital, Division of Renal Medicine - Site #379 | Boston | Massachusetts | 21155 | — |
| Tufts Medical Center - Site #349 | Boston | Massachusetts | 21277 | — |
| Beth Israel Deaconess Medical Center - Site #337 | Boston | Massachusetts | 22155 | — |
| UMASS Memorial Medical Center - Site #331 | Worcester | Massachusetts | 01655 | — |
| UMASS Memorial Medical Center - Site #331 | Worcester | Massachusetts | 16555 | — |
| St. Clair Nephrology Research - Site #320 | Roseville | Michigan | 48066 | — |
| University of Minnesota - Site #345 | Minneapolis | Minnesota | 55414 | — |
| Mayo Clinic - Rochester - Site #332 | Rochester | Minnesota | 55905 | — |
| University of Nebraska Medical Center - Site #347 | Omaha | Nebraska | 68198 | — |
| Davita Clinical Research - Las Vegas - Site #327 | Las Vegas | Nevada | 89107 | — |
| Northwell Health - North Shore University Hospital NSUH - Site #346 | Great Neck | New York | 11021 | — |
| New York University Grossman School of Medicine - Site #362 | New York | New York | 10016 | — |
| Jacobi Medical Center - Site #364 | The Bronx | New York | 10461 | — |
| The University of Cincinnati - Site #343 | Cincinnati | Ohio | 45267 | — |
| The Ohio State University Wexner Medical Center - Site #350 | Columbus | Ohio | 43210 | — |
| Rhode Island Hospital - Site #367 | Providence | Rhode Island | 02903 | — |
| Rhode Island Hospital - Site #367 | Providence | Rhode Island | 29033 | — |
| Dunes Clinical Research LLC - Site #374 | Dakota Dunes | South Dakota | 57029 | — |
| Research Management, Inc - Site #354 | Austin | Texas | 78751 | — |
| Renal Disease Research Institute - Site #378 | Dallas | Texas | 75235 | — |
| Baylor College of Medicine (BCM) Medical Center - Site #375 | Houston | Texas | 77030 | — |
| Prolato Clinical Research Center (PCRC) - Site #324 | Houston | Texas | 77054 | — |
| Pioneer Research Solutions, Inc. - Site #339 | Houston | Texas | 77099 | — |
| UT Health Science Center at San Antonio - Site #368 | San Antonio | Texas | 78229 | — |
| Utah Kidney Research Institute - Site #342 | Salt Lake City | Utah | 84115 | — |
| University of Wisconsin - Site #352 | Madison | Wisconsin | 53717 | — |
| Medical College of Wisconsin - Site #361 | Milwaukee | Wisconsin | 53213 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 254 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05248646, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 13, 2026 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05248646 live on ClinicalTrials.gov.