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Enrolling by invitation Phase 2Phase 3 Interventional

Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy (IgAN)

ClinicalTrials.gov ID: NCT05248659

Public ClinicalTrials.gov record NCT05248659. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2/3, Multicenter, Open-label Trial to Evaluate the Long-term Safety, Tolerability, and Efficacy of Sibeprenlimab Administered Subcutaneously in Subjects With Immunoglobulin A Nephropathy.

Study identification

NCT ID
NCT05248659
Recruitment status
Enrolling by invitation
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Enrollment
600 participants

Conditions and interventions

Interventions

  • Sibeprenlimab 400 mg s.c. Q4weeks Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 4, 2022
Primary completion
Dec 27, 2028
Completion
Dec 30, 2029
Last update posted
May 4, 2026

2022 – 2029

United States locations

U.S. sites
15
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Clinical Research Site #336 Birmingham Alabama 35233
Clinical Research Site #325 Los Angeles California 90027
Clinical Research Site #370 Palo Alto California 94304
Clinical Research Site #330 Denver Colorado 80220
Clinical Research Site #323 Lauderdale Lakes Florida 33313
Clinical Research Site #373 Atlanta Georgia 30342
Clinical Research Site #356 Lawrenceville Georgia 30046
Clinical Research Site #369 Boston Massachusetts 02114
Clinical Research Site #331 Worcester Massachusetts 01655
Clinical Research Site #320 Shelby Michigan 48315
Clinical Research Site #346 Great Neck New York 11021
Clinical Research Site #350 Columbus Ohio 43210
Clinical Research Site #374 Dakota Dunes South Dakota 57029
Clinical Research Site #324 Houston Texas 77030
Clinical Research Site #361 Milwaukee Wisconsin 53213

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 143 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05248659, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 4, 2026 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05248659 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →