Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-Severe Uncontrolled Asthma
Public ClinicalTrials.gov record NCT05251259. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomised, Double-Blind, Placebo-Controlled Study to Assess Efficacy and Safety of Atuliflapon Given Orally Once Daily for Twelve Weeks in Adults With Moderate to Severe Uncontrolled Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomised, placebo-controlled, double-blind study to assess the efficacy and safety of Atuliflapon administered once daily over a 12-week treatment period to adult participants with moderate to severe uncontrolled asthma.
Study identification
- NCT ID
- NCT05251259
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 670 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 27, 2022 (Actual)
- Primary completion
- Jan 7, 2026 (Actual)
- Completion
- Jan 7, 2026 (Actual)
- Last update posted
- Jan 14, 2026
2022 – 2026
United States locations
- U.S. sites
- 64
- U.S. states
- 22
- U.S. cities
- 55
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35211 | — |
| Research Site | Sheffield | Alabama | 35660 | — |
| Research Site | Phoenix | Arizona | 85020 | — |
| Research Site | Tucson | Arizona | 85741 | — |
| Research Site | Little Rock | Arkansas | 72212 | — |
| Research Site | Bakersfield | California | 93301 | — |
| Research Site | Fountain Valley | California | 92708 | — |
| Research Site | Huntington Beach | California | 92647 | — |
| Research Site | Los Angeles | California | 90025 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | San Jose | California | 95117 | — |
| Research Site | Valencia | California | 91355 | — |
| Research Site | Colorado Springs | Colorado | 80907 | — |
| Research Site | Cutler Bay | Florida | 33157 | — |
| Research Site | Cutler Bay | Florida | 33189 | — |
| Research Site | Hialeah | Florida | 33012 | — |
| Research Site | Hialeah | Florida | 33015 | — |
| Research Site | Hialeah | Florida | 33016 | — |
| Research Site | Miami | Florida | 33125 | — |
| Research Site | Miami | Florida | 33155 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site | Miami | Florida | 33174 | — |
| Research Site | Orlando | Florida | 32807 | — |
| Research Site | Tampa | Florida | 33613 | — |
| Research Site | Tampa | Florida | 33615 | — |
| Research Site | Fayetteville | Georgia | 30214 | — |
| Research Site | Lithonia | Georgia | 30038 | — |
| Research Site | Savannah | Georgia | 31406 | — |
| Research Site | Boise | Idaho | 83706 | — |
| Research Site | Lexington | Kentucky | 40509 | — |
| Research Site | Owensboro | Kentucky | 42301 | — |
| Research Site | Oxon Hill | Maryland | 20745 | — |
| Research Site | New Bedford | Massachusetts | 02740 | — |
| Research Site | Ann Arbor | Michigan | 48105 | — |
| Research Site | Farmington Hills | Michigan | 48336 | — |
| Research Site | Saint Charles | Missouri | 63301 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | East Orange | New Jersey | 07018 | — |
| Research Site | Toms River | New Jersey | 08755 | — |
| Research Site | The Bronx | New York | 10459 | — |
| Research Site | Valhalla | New York | 10595 | — |
| Research Site | Charlotte | North Carolina | 28210 | — |
| Research Site | Charlotte | North Carolina | 28287 | — |
| Research Site | Gastonia | North Carolina | 28054 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Blue Ash | Ohio | 45242 | — |
| Research Site | Dayton | Ohio | 45439 | — |
| Research Site | Edmond | Oklahoma | 73034 | — |
| Research Site | Pittsburgh | Pennsylvania | 15241 | — |
| Research Site | Columbia | South Carolina | 29204 | — |
| Research Site | Greenville | South Carolina | 29615 | — |
| Research Site | Spartanburg | South Carolina | 29303 | — |
| Research Site | Austin | Texas | 78705 | — |
| Research Site | Beaumont | Texas | 77701 | — |
| Research Site | Bellaire | Texas | 77401 | — |
| Research Site | Dallas | Texas | 75225 | — |
| Research Site | El Paso | Texas | 79902 | — |
| Research Site | El Paso | Texas | 79903 | — |
| Research Site | Houston | Texas | 77022 | — |
| Research Site | McKinney | Texas | 75069 | — |
| Research Site | San Antonio | Texas | 78258 | — |
| Research Site | Sugar Land | Texas | 77479 | — |
| Research Site | Tomball | Texas | 77375 | — |
| Research Site | Milwaukee | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 170 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05251259, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 14, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05251259 live on ClinicalTrials.gov.