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Terminated Phase 1 Interventional

Assess Safety and Tolerability of ART-123 + FOLFOX + Bevacizumab in Metastatic Colorectal Cancer Patients

ClinicalTrials.gov ID: NCT05251727

Public ClinicalTrials.gov record NCT05251727. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 8:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Double-blind, Placebo-controlled, Randomized, Dose-escalating, Multi-center, Phase 1 Study to Assess the Safety and Tolerability of ART-123 With Leucovorin/5-fluorouracil/Oxaliplatin and Bevacizumab in Metastatic Colorectal Cancer Patients

Study identification

NCT ID
NCT05251727
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Veloxis Pharmaceuticals
Industry
Enrollment
77 participants

Conditions and interventions

Interventions

  • thrombomodulin alfa Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 23, 2022
Primary completion
Jun 4, 2024
Completion
Jun 4, 2024
Last update posted
Aug 18, 2024

2022 – 2024

United States locations

U.S. sites
18
U.S. states
15
U.S. cities
18
Facility City State ZIP Site status
Beverly Hills Cancer Center Beverly Hills California 90210
UCLA Dept. of Medicine - Hematology/Oncology Los Angeles California 90095
Eastern Connecticut Hematology & Oncology Associates Norwich Connecticut 06360
Mid-Florida Hematology & Oncology Centers Orange City Florida 32763
Horizon Oncology Research, Inc. Lafayette Indiana 47905
American Oncology Partners, P.A. Bethesda Maryland 20817
Tufts Medical Center Boston Massachusetts 02111
Henry Ford Health System Detroit Michigan 48202
St. Vincent Frontier Cancer Center Billings Montana 59101
Englewood Hospital and Medical Center Englewood New Jersey 07631
Site #115 Hackensack New Jersey 07601
Memorial Sloan Kettering Cancer Center New York New York 10065
Oregon Health & Science University Portland Oregon 97239
Prisma Health Cancer Institute Greenville South Carolina 29605
Nashville Oncology Associates, PC Nashville Tennessee 37203
Site #120 Dallas Texas 75230
Site #114 Houston Texas 77024
MultiCare Regional Cancer Center Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05251727, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 18, 2024 · Synced Jun 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05251727 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →