ClinicalTrials.gov record
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
ClinicalTrials.gov ID: NCT05256225
Public ClinicalTrials.gov record NCT05256225. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops tumor cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial cancer.
Study identification
- NCT ID
- NCT05256225
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 360 participants
Conditions and interventions
Conditions
- Endometrial Carcinoma
- Endometrial Clear Cell Adenocarcinoma
- Endometrial Dedifferentiated Carcinoma
- Endometrial Endometrioid Adenocarcinoma
- Endometrial Mixed Cell Adenocarcinoma
- Endometrial Serous Adenocarcinoma
- Endometrial Undifferentiated Carcinoma
- Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor
Interventions
- Biospecimen Collection Procedure
- Carboplatin Drug
- Computed Tomography Procedure
- Echocardiography Test Procedure
- High-Dose-Rate Vaginal Cuff Brachytherapy Radiation
- Hyaluronidase-zzxf/Pertuzumab/Trastuzumab Drug
- Multigated Acquisition Scan Procedure
- Paclitaxel Drug
- Survey Administration Other
- Trastuzumab/Hyaluronidase-oysk Drug
Procedure · Drug · Radiation + 1 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 16, 2022 (Actual)
- Primary completion
- Oct 31, 2027 (Estimated)
- Completion
- Oct 31, 2027 (Estimated)
- Last update posted
- Oct 2, 2026
2022 – 2027
United States locations
- U.S. sites
- 409
- U.S. states
- 47
- U.S. cities
- 310
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | — |
| Banner University Medical Center - Tucson | Tucson | Arizona | 85719 | — |
| University of Arizona Cancer Center-North Campus | Tucson | Arizona | 85719 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Sutter Auburn Faith Hospital | Auburn | California | 95602 | — |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | 94704 | — |
| John Muir Medical Center-Concord | Concord | California | 94520 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| City of Hope Seacliff | Huntington Beach | California | 92648 | — |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | Irvine | California | 92612 | — |
| City of Hope at Irvine Lennar | Irvine | California | 92618 | — |
| Kaiser Permanente-Irvine | Irvine | California | 92618 | — |
| City of Hope at Long Beach Elm | Long Beach | California | 90813 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View | California | 94040 | — |
| Saint Joseph Hospital - Orange | Orange | California | 92868 | — |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| Stanford Cancer Institute Palo Alto | Palo Alto | California | 94304 | — |
| Kaiser Permanente - Panorama City | Panorama City | California | 91402 | — |
| Kaiser Permanente-Riverside | Riverside | California | 92505 | — |
| Sutter Roseville Medical Center | Roseville | California | 95661 | — |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| Palo Alto Medical Foundation-Santa Cruz | Santa Cruz | California | 95065 | — |
| Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | 94086 | — |
| City of Hope Upland | Upland | California | 91786 | — |
| John Muir Medical Center-Walnut Creek | Walnut Creek | California | 94598 | — |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| UCHealth - Cherry Creek | Denver | Colorado | 80206 | — |
| AdventHealth Porter | Denver | Colorado | 80210 | — |
| Grand Valley Oncology | Grand Junction | Colorado | 81505 | — |
| Banner North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| UCHealth Highlands Ranch Hospital | Highlands Ranch | Colorado | 80129 | — |
| Banner North Colorado Medical Center - Loveland Campus | Loveland | Colorado | 80539 | — |
| Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Smilow Cancer Hospital-Derby Care Center | Derby | Connecticut | 06418 | — |
| Smilow Cancer Hospital Care Center-Fairfield | Fairfield | Connecticut | 06824 | — |
| Smilow Cancer Hospital Care Center at Glastonbury | Glastonbury | Connecticut | 06033 | — |
| Smilow Cancer Hospital Care Center at Greenwich | Greenwich | Connecticut | 06830 | — |
| Smilow Cancer Hospital Care Center - Guilford | Guilford | Connecticut | 06437 | — |
| Smilow Cancer Hospital Care Center at Saint Francis | Hartford | Connecticut | 06105 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Yale-New Haven Hospital North Haven Medical Center | North Haven | Connecticut | 06473 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Smilow Cancer Hospital Care Center at Long Ridge | Stamford | Connecticut | 06902 | — |
| Smilow Cancer Hospital-Torrington Care Center | Torrington | Connecticut | 06790 | — |
| Smilow Cancer Hospital Care Center-Trumbull | Trumbull | Connecticut | 06611 | — |
| Smilow Cancer Hospital-Waterbury Care Center | Waterbury | Connecticut | 06708 | — |
| Smilow Cancer Hospital Care Center - Waterford | Waterford | Connecticut | 06385 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Medical Oncology Hematology Consultants PA | Newark | Delaware | 19713 | — |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | — |
| George Washington University Medical Center | Washington D.C. | District of Columbia | 20037 | — |
| Broward Health Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Jupiter Medical Center | Jupiter | Florida | 33458 | — |
| Sarasota Memorial Hospital-Venice | N. Venice | Florida | 34275 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Florida Cancer Specialists - Sarasota Downtown | Sarasota | Florida | 34239 | — |
| FPG - Surgical Oncology Clinics Gynecologic Oncology Surgery | Sarasota | Florida | 34239 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Florida Cancer Specialists - Venice Pinebrook | Venice | Florida | 34275 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| Emory Decatur Hospital | Decatur | Georgia | 30033 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | — |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | — |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | — |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | — |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | — |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83687 | — |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | — |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | — |
| Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | 83301 | — |
| Northwest Community Hospital | Arlington Heights | Illinois | 60005 | — |
| Rush-Copley Medical Center | Aurora | Illinois | 60504 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Rush MD Anderson Cancer Center | Chicago | Illinois | 60612 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Northwestern Medicine Cancer Center Kishwaukee | DeKalb | Illinois | 60115 | — |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois | 60201 | — |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | — |
| NorthShore University HealthSystem-Glenbrook Hospital | Glenview | Illinois | 60026 | — |
| Northwestern Medicine Glenview Outpatient Center | Glenview | Illinois | 60026 | — |
| Northwestern Medicine Grayslake Outpatient Center | Grayslake | Illinois | 60030 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| NorthShore University HealthSystem-Highland Park Hospital | Highland Park | Illinois | 60035 | — |
| Sudarshan K Sharma MD Limited-Gynecologic Oncology | Hinsdale | Illinois | 60521 | — |
| Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | 60045 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| UC Comprehensive Cancer Center at Silver Cross | New Lenox | Illinois | 60451 | — |
| Carle Cancer Institute Normal | Normal | Illinois | 61761 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| Northwestern Medicine Orland Park | Orland Park | Illinois | 60462 | — |
| University of Chicago Medicine-Orland Park | Orland Park | Illinois | 60462 | — |
| UW Health Carbone Cancer Center Rockford | Rockford | Illinois | 61114 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | — |
| Rush-Copley Healthcare Center | Yorkville | Illinois | 60560 | — |
| IU Health North Hospital | Carmel | Indiana | 46032 | — |
| Northwest Cancer Center - Crown Point | Crown Point | Indiana | 46307 | — |
| UChicago Medicine Northwest Indiana | Crown Point | Indiana | 46307 | — |
| Northwest Oncology LLC | Dyer | Indiana | 46311 | — |
| Goshen Center for Cancer Care | Goshen | Indiana | 46526 | — |
| Northwest Cancer Center - Hobart | Hobart | Indiana | 46342 | — |
| Saint Mary Medical Center | Hobart | Indiana | 46342 | — |
| Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Franciscan Health Indianapolis | Indianapolis | Indiana | 46237 | — |
| Ascension Saint Vincent Indianapolis Hospital | Indianapolis | Indiana | 46260 | — |
| Saint Catherine Hospital | Indianapolis | Indiana | 46312 | — |
| Franciscan Saint Elizabeth Health - Lafayette East | Lafayette | Indiana | 47905 | — |
| Franciscan Health Mooresville | Mooresville | Indiana | 46158 | — |
| The Community Hospital | Munster | Indiana | 46321 | — |
| Women's Diagnostic Center - Munster | Munster | Indiana | 46321 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Northwest Cancer Center - Valparaiso | Valparaiso | Indiana | 46383 | — |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | — |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | — |
| McFarland Clinic - Boone | Boone | Iowa | 50036 | — |
| Heartland Oncology and Hematology LLP | Council Bluffs | Iowa | 51503 | — |
| Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ | Council Bluffs | Iowa | 51503 | — |
| McFarland Clinic - Trinity Cancer Center | Fort Dodge | Iowa | 50501 | — |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| McFarland Clinic - Jefferson | Jefferson | Iowa | 50129 | — |
| McFarland Clinic - Marshalltown | Marshalltown | Iowa | 50158 | — |
| AdventHealth Shawnee Mission | Shawnee Mission | Kansas | 66204 | — |
| Saint Elizabeth Healthcare Edgewood | Edgewood | Kentucky | 41017 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Baptist Health Louisville | Louisville | Kentucky | 40207 | — |
| LSU Health Baton Rouge-North Clinic | Baton Rouge | Louisiana | 70805 | — |
| Our Lady of the Lake Physician Group | Baton Rouge | Louisiana | 70808 | — |
| Our Lady of the Lake Medical Oncology | Baton Rouge | Louisiana | 70817 | — |
| Ochsner Hematology Oncology North Shore - Covington (West Region) | Covington | Louisiana | 70433 | — |
| West Jefferson Medical Center | Marrero | Louisiana | 70072 | — |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | — |
| LSU Healthcare Network / Metairie Multi-Specialty Clinic | Metairie | Louisiana | 70006 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Ochsner Baptist Medical Center | New Orleans | Louisiana | 70115 | — |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| MaineHealth Maine Medical Center- Scarborough | Scarborough | Maine | 04074 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| MedStar Franklin Square Medical Center/Weinberg Cancer Institute | Baltimore | Maryland | 21237 | — |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Baltimore | Maryland | 21287 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889-5600 | — |
| William E Kahlert Regional Cancer Center/Sinai Hospital | Westminster | Maryland | 21157 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Michigan Rogel Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Bronson Battle Creek | Battle Creek | Michigan | 49017 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | 48114 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | 48188 | — |
| Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | 48118 | — |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | — |
| Corewell Health Farmington Hills Hospital | Farmington Hills | Michigan | 48336 | — |
| Cancer Hematology Centers - Flint | Flint | Michigan | 48503 | — |
| Genesee Hematology Oncology PC | Flint | Michigan | 48503 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital | Grand Rapids | Michigan | 49503 | — |
| Trinity Health Grand Rapids Hospital | Grand Rapids | Michigan | 49503 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Beacon Kalamazoo Cancer Center | Kalamazoo | Michigan | 49009 | — |
| University of Michigan Health - Sparrow Lansing | Lansing | Michigan | 48912 | — |
| Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | 48154 | — |
| Trinity Health Muskegon Hospital | Muskegon | Michigan | 49444 | — |
| Corewell Health Lakeland Hospitals - Niles Hospital | Niles | Michigan | 49120 | — |
| Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | 49444 | — |
| Trinity Health Saint Joseph Mercy Oakland Hospital | Pontiac | Michigan | 48341 | — |
| Corewell Health Reed City Hospital | Reed City | Michigan | 49677 | — |
| Corewell Health William Beaumont University Hospital | Royal Oak | Michigan | 48073 | — |
| MyMichigan Medical Center Saginaw | Saginaw | Michigan | 48601 | — |
| Oncology Hematology Associates of Saginaw Valley PC | Saginaw | Michigan | 48604 | — |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center | Saint Joseph | Michigan | 49085 | — |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital | Saint Joseph | Michigan | 49085 | — |
| MyMichigan Medical Center Tawas | Tawas City | Michigan | 48764 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| Corewell Health Beaumont Troy Hospital | Troy | Michigan | 48085 | — |
| Saint Mary's Oncology/Hematology Associates of West Branch | West Branch | Michigan | 48661 | — |
| University of Michigan Health - West | Wyoming | Michigan | 49519 | — |
| Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | 48197 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Minnesota Oncology - Edina | Edina | Minnesota | 55435 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Avera Cancer Institute at Marshall | Marshall | Minnesota | 56258 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| MU Health - University Hospital/Ellis Fischel Cancer Center | Columbia | Missouri | 65212 | — |
| Phelps Health Delbert Day Cancer Institute | Rolla | Missouri | 65401 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Mercy Hospital South | St Louis | Missouri | 63128 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | — |
| Saint Vincent Frontier Cancer Center | Billings | Montana | 59102 | — |
| Intermountain Health West End Clinic | Billings | Montana | 59106 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Logan Health Medical Center | Kalispell | Montana | 59901 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Community Medical Center | Missoula | Montana | 59804 | — |
| Nebraska Cancer Specialists/Oncology Hematology West PC - MECC | Omaha | Nebraska | 68114 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| OptumCare Cancer Care at Charleston | Las Vegas | Nevada | 89102 | — |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89106 | — |
| OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | 89183 | — |
| Memorial Sloan Kettering Basking Ridge | Basking Ridge | New Jersey | 07920 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Monmouth Medical Center Southern Campus | Lakewood | New Jersey | 08701 | — |
| Cooperman Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Memorial Sloan Kettering Monmouth | Middletown | New Jersey | 07748 | — |
| Memorial Sloan Kettering Bergen | Montvale | New Jersey | 07645 | — |
| Virtua Samson Cancer Center | Moorestown | New Jersey | 08057 | — |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07753 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07101 | — |
| Riverview Medical Center/Booker Cancer Center | Red Bank | New Jersey | 07701 | — |
| Sidney Kimmel Cancer Center Washington Township | Sewell | New Jersey | 08080 | — |
| Robert Wood Johnson University Hospital Somerset | Somerville | New Jersey | 08876 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| Virtua Voorhees | Voorhees Township | New Jersey | 08043 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| Presbyterian Kaseman Hospital | Albuquerque | New Mexico | 87110 | — |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho | New Mexico | 87124 | — |
| Women's Cancer Care Associates LLC | Albany | New York | 12208 | — |
| Memorial Sloan Kettering Commack | Commack | New York | 11725 | — |
| Memorial Sloan Kettering Westchester | Harrison | New York | 10604 | — |
| NYU Langone Hospital - Long Island | Mineola | New York | 11501 | — |
| Mount Sinai Chelsea | New York | New York | 10011 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | — |
| Montefiore Medical Center-Weiler Hospital | The Bronx | New York | 10461 | — |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | — |
| Memorial Sloan Kettering Nassau | Uniondale | New York | 11553 | — |
| Wilmot Cancer Institute at Webster | Webster | New York | 14580 | — |
| Duke Cancer Center Cary | Cary | North Carolina | 27518 | — |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| ECU Health Medical Center | Greenville | North Carolina | 27834 | — |
| Hayworth Cancer Center | High Point | North Carolina | 27262 | — |
| Duke Women's Cancer Care Raleigh | Raleigh | North Carolina | 27607 | — |
| Novant Health New Hanover Regional Medical Center | Wilmington | North Carolina | 28401 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| UHHS-Chagrin Highlands Medical Center | Beachwood | Ohio | 44122 | — |
| Strecker Cancer Center-Belpre | Belpre | Ohio | 45714 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | — |
| Geauga Hospital | Chardon | Ohio | 44024 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Mount Carmel East Hospital | Columbus | Ohio | 43213 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| The Mark H Zangmeister Center | Columbus | Ohio | 43219 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Miami Valley Hospital North | Dayton | Ohio | 45415 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Miami Valley Cancer Care and Infusion | Greenville | Ohio | 45331 | — |
| Mount Carmel Grove City Hospital | Grove City | Ohio | 43123 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Saint Rita's Medical Center | Lima | Ohio | 45801 | — |
| Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Memorial Hospital | Marysville | Ohio | 43040 | — |
| UH Seidman Cancer Center at Lake Health Mentor Campus | Mentor | Ohio | 44060 | — |
| Knox Community Hospital | Mount Vernon | Ohio | 43050 | — |
| Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| University Hospitals Parma Medical Center | Parma | Ohio | 44129 | — |
| Mercy Health - Perrysburg Hospital | Perrysburg | Ohio | 43551 | — |
| Southern Ohio Medical Center | Portsmouth | Ohio | 45662 | — |
| Springfield Regional Cancer Center | Springfield | Ohio | 45504 | — |
| Springfield Regional Medical Center | Springfield | Ohio | 45504 | — |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | — |
| Mercy Health - Saint Vincent Hospital | Toledo | Ohio | 43608 | — |
| Mercy Health - Saint Anne Hospital | Toledo | Ohio | 43623 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Saint Ann's Hospital | Westerville | Ohio | 43081 | — |
| UH Seidman Cancer Center at Saint John Medical Center | Westlake | Ohio | 44145 | — |
| Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | 43701 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma | 74146 | — |
| Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | 97015 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Saint Alphonsus Cancer Care Center-Ontario | Ontario | Oregon | 97914 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| Saint Luke's Cancer Center - Allentown | Allentown | Pennsylvania | 18104 | — |
| Saint Luke's University Hospital-Bethlehem Campus | Bethlehem | Pennsylvania | 18015 | — |
| Lehigh Valley Hospital - Muhlenberg | Bethlehem | Pennsylvania | 18017 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | — |
| Saint Luke's Hospital-Anderson Campus | Easton | Pennsylvania | 18045 | — |
| Saint Vincent Hospital | Erie | Pennsylvania | 16544 | — |
| Lehigh Valley Hospital-Hazleton | Hazleton | Pennsylvania | 18201 | — |
| Jefferson Hospital | Jefferson Hills | Pennsylvania | 15025 | — |
| Riddle Memorial Hospital | Media | Pennsylvania | 19063 | — |
| Forbes Hospital | Monroeville | Pennsylvania | 15146 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Saint Luke's Hospital - Upper Bucks Campus | Quakertown | Pennsylvania | 18951 | — |
| Chester County Hospital | West Chester | Pennsylvania | 19380 | — |
| Wexford Health and Wellness Pavilion | Wexford | Pennsylvania | 15090 | — |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Women and Infants Hospital | Providence | Rhode Island | 02905 | — |
| Smilow Cancer Hospital Care Center - Westerly | Westerly | Rhode Island | 02891 | — |
| Saint Joseph's/Candler - Bluffton Campus | Bluffton | South Carolina | 29910 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Avera Cancer Institute-Aberdeen | Aberdeen | South Dakota | 57401 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | — |
| The West Clinic - Wolf River | Germantown | Tennessee | 38138 | — |
| Dell Seton Medical Center at The University of Texas | Austin | Texas | 78701 | — |
| University of Texas at Austin | Austin | Texas | 78712 | — |
| Parkland Memorial Hospital | Dallas | Texas | 75235 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| Tarrant County Hospital District/JPS Health Network | Fort Worth | Texas | 76104 | — |
| UT Southwestern/Simmons Cancer Center-Fort Worth | Fort Worth | Texas | 76104 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Memorial Hermann Texas Medical Center | Houston | Texas | 77030 | — |
| Methodist Willowbrook Hospital | Houston | Texas | 77070 | — |
| Houston Methodist West Hospital | Houston | Texas | 77094 | — |
| Houston Methodist Saint John Hospital | Nassau Bay | Texas | 77058 | — |
| UT Southwestern Clinical Center at Richardson/Plano | Richardson | Texas | 75080 | — |
| Houston Methodist Sugar Land Hospital | Sugar Land | Texas | 77479 | — |
| Houston Methodist The Woodlands Hospital | The Woodlands | Texas | 77385 | — |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | — |
| South Jordan Health Center | South Jordan | Utah | 84009 | — |
| University of Virginia Cancer Center | Charlottesville | Virginia | 22908 | — |
| Henrico Doctor's Hospital | Richmond | Virginia | 23229 | — |
| VCU Massey Cancer Center at Stony Point | Richmond | Virginia | 23235 | — |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | — |
| Carilion Roanoke Memorial Hospital | Roanoke | Virginia | 24033 | — |
| Swedish Cancer Institute-Edmonds | Edmonds | Washington | 98026 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| Legacy Salmon Creek Hospital | Vancouver | Washington | 98686 | — |
| Vandalia Health/CAMC Institute for Academic Medicine | Charleston | West Virginia | 25304 | — |
| West Virginia University Healthcare | Morgantown | West Virginia | 26506 | — |
| Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | 54701 | — |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Madison | Wisconsin | 53718 | — |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Marshfield Medical Center - Minocqua | Minocqua | Wisconsin | 54548 | — |
| ProHealth D N Greenwald Center | Mukwonago | Wisconsin | 53149 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | 54868 | — |
| Saint Vincent Hospital Cancer Center at Sheboygan | Sheboygan | Wisconsin | 53081 | — |
| Sheboygan Physicians Group | Sheboygan | Wisconsin | 53081 | — |
| Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | 54482 | — |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235-1495 | — |
| UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | 53188 | — |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05256225, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 2, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05256225 live on ClinicalTrials.gov.