Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

ClinicalTrials.gov ID: NCT05256225

Public ClinicalTrials.gov record NCT05256225. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 10:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma

Study identification

NCT ID: NCT05256225
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: National Cancer Institute (NCI); NIH
Enrollment: 360 participants

Conditions and interventions

Conditions

Interventions

Biospecimen Collection Procedure
Carboplatin Drug
Computed Tomography Procedure
Echocardiography Test Procedure
High-Dose-Rate Vaginal Cuff Brachytherapy Radiation
Hyaluronidase-zzxf/Pertuzumab/Trastuzumab Drug
Multigated Acquisition Scan Procedure
Paclitaxel Drug
Survey Administration Other
Trastuzumab/Hyaluronidase-oysk Drug

Procedure · Drug · Radiation + 1 more

Eligibility (public fields only)

Age range: 18 Years and older
Sex: Female
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 15, 2022
Primary completion: Oct 30, 2027
Completion: Oct 30, 2027
Last update posted: May 5, 2026

2022 – 2027

United States locations

U.S. sites: 403
U.S. states: 46
U.S. cities: 307

Facility	City	State	ZIP	Site status
University of Alabama at Birmingham Cancer Center	Birmingham	Alabama	35233	Recruiting
Alaska Women's Cancer Care	Anchorage	Alaska	99508	Recruiting
Banner University Medical Center - Tucson	Tucson	Arizona	85719	Recruiting
University of Arizona Cancer Center-North Campus	Tucson	Arizona	85719	Recruiting
University of Arkansas for Medical Sciences	Little Rock	Arkansas	72205	Recruiting
Sutter Auburn Faith Hospital	Auburn	California	95602	Recruiting
Alta Bates Summit Medical Center-Herrick Campus	Berkeley	California	94704	Recruiting
John Muir Medical Center-Concord	Concord	California	94520	Active, not recruiting
City of Hope Comprehensive Cancer Center	Duarte	California	91010	Active, not recruiting
City of Hope Seacliff	Huntington Beach	California	92648	Active, not recruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care	Irvine	California	92612	Recruiting
City of Hope at Irvine Lennar	Irvine	California	92618	Active, not recruiting
Kaiser Permanente-Irvine	Irvine	California	92618	Recruiting
City of Hope at Long Beach Elm	Long Beach	California	90813	Active, not recruiting
Kaiser Permanente Los Angeles Medical Center	Los Angeles	California	90027	Recruiting
Memorial Medical Center	Modesto	California	95355	Recruiting
Palo Alto Medical Foundation-Gynecologic Oncology	Mountain View	California	94040	Suspended
Saint Joseph Hospital - Orange	Orange	California	92868	Recruiting
UC Irvine Health/Chao Family Comprehensive Cancer Center	Orange	California	92868	Recruiting
Stanford Cancer Institute Palo Alto	Palo Alto	California	94304	Recruiting
Kaiser Permanente - Panorama City	Panorama City	California	91402	Recruiting
Kaiser Permanente-Riverside	Riverside	California	92505	Recruiting
Sutter Roseville Medical Center	Roseville	California	95661	Recruiting
Sutter Medical Center Sacramento	Sacramento	California	95816	Recruiting
University of California Davis Comprehensive Cancer Center	Sacramento	California	95817	Recruiting
California Pacific Medical Center-Pacific Campus	San Francisco	California	94115	Recruiting
Palo Alto Medical Foundation-Santa Cruz	Santa Cruz	California	95065	Recruiting
Palo Alto Medical Foundation-Sunnyvale	Sunnyvale	California	94086	Recruiting
City of Hope Upland	Upland	California	91786	Active, not recruiting
John Muir Medical Center-Walnut Creek	Walnut Creek	California	94598	Recruiting
UCHealth University of Colorado Hospital	Aurora	Colorado	80045	Recruiting
UCHealth - Cherry Creek	Denver	Colorado	80206	Recruiting
AdventHealth Porter	Denver	Colorado	80210	Recruiting
Grand Valley Oncology	Grand Junction	Colorado	81505	Recruiting
Banner North Colorado Medical Center	Greeley	Colorado	80631	Recruiting
UCHealth Highlands Ranch Hospital	Highlands Ranch	Colorado	80129	Recruiting
Banner North Colorado Medical Center - Loveland Campus	Loveland	Colorado	80539	Recruiting
Danbury Hospital	Danbury	Connecticut	06810	Recruiting
Smilow Cancer Hospital-Derby Care Center	Derby	Connecticut	06418	Recruiting
Smilow Cancer Hospital Care Center-Fairfield	Fairfield	Connecticut	06824	Recruiting
Smilow Cancer Hospital Care Center at Glastonbury	Glastonbury	Connecticut	06033	Recruiting
Smilow Cancer Hospital Care Center at Greenwich	Greenwich	Connecticut	06830	Recruiting
Smilow Cancer Hospital Care Center - Guilford	Guilford	Connecticut	06437	Recruiting
Smilow Cancer Hospital Care Center at Saint Francis	Hartford	Connecticut	06105	Recruiting
Yale University	New Haven	Connecticut	06520	Recruiting
Yale-New Haven Hospital North Haven Medical Center	North Haven	Connecticut	06473	Recruiting
Norwalk Hospital	Norwalk	Connecticut	06856	Recruiting
Smilow Cancer Hospital Care Center at Long Ridge	Stamford	Connecticut	06902	Recruiting
Smilow Cancer Hospital-Torrington Care Center	Torrington	Connecticut	06790	Recruiting
Smilow Cancer Hospital Care Center-Trumbull	Trumbull	Connecticut	06611	Recruiting
Smilow Cancer Hospital-Waterbury Care Center	Waterbury	Connecticut	06708	Recruiting
Smilow Cancer Hospital Care Center - Waterford	Waterford	Connecticut	06385	Recruiting
Helen F Graham Cancer Center	Newark	Delaware	19713	Recruiting
Medical Oncology Hematology Consultants PA	Newark	Delaware	19713	Recruiting
Sibley Memorial Hospital	Washington D.C.	District of Columbia	20016	Recruiting
George Washington University Medical Center	Washington D.C.	District of Columbia	20037	Recruiting
Broward Health Medical Center	Fort Lauderdale	Florida	33316	Recruiting
Jupiter Medical Center	Jupiter	Florida	33458	Active, not recruiting
Sarasota Memorial Hospital-Venice	N. Venice	Florida	34275	Recruiting
AdventHealth Orlando	Orlando	Florida	32803	Recruiting
Florida Cancer Specialists - Sarasota Downtown	Sarasota	Florida	34236	Recruiting
First Physicians Group-Sarasota	Sarasota	Florida	34239	Recruiting
Sarasota Memorial Hospital	Sarasota	Florida	34239	Recruiting
Florida Cancer Specialists - Venice Pinebrook	Venice	Florida	34275	Recruiting
Grady Health System	Atlanta	Georgia	30303	Recruiting
Emory University Hospital Midtown	Atlanta	Georgia	30308	Recruiting
Piedmont Hospital	Atlanta	Georgia	30309	Recruiting
Emory University Hospital/Winship Cancer Institute	Atlanta	Georgia	30322	Recruiting
Emory Saint Joseph's Hospital	Atlanta	Georgia	30342	Recruiting
Augusta University Medical Center	Augusta	Georgia	30912	Recruiting
Emory Decatur Hospital	Decatur	Georgia	30033	Recruiting
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler	Savannah	Georgia	31405	Recruiting
Queen's Medical Center	Honolulu	Hawaii	96813	Recruiting
Kapiolani Medical Center for Women and Children	Honolulu	Hawaii	96826	Recruiting
Saint Alphonsus Cancer Care Center-Boise	Boise	Idaho	83706	Recruiting
Saint Luke's Cancer Institute - Boise	Boise	Idaho	83712	Recruiting
Saint Alphonsus Cancer Care Center-Caldwell	Caldwell	Idaho	83605	Recruiting
Kootenai Health - Coeur d'Alene	Coeur d'Alene	Idaho	83814	Recruiting
Saint Luke's Cancer Institute - Fruitland	Fruitland	Idaho	83619	Recruiting
Saint Luke's Cancer Institute - Meridian	Meridian	Idaho	83642	Recruiting
Saint Alphonsus Cancer Care Center-Nampa	Nampa	Idaho	83687	Recruiting
Saint Luke's Cancer Institute - Nampa	Nampa	Idaho	83687	Recruiting
Kootenai Clinic Cancer Services - Post Falls	Post Falls	Idaho	83854	Recruiting
Kootenai Clinic Cancer Services - Sandpoint	Sandpoint	Idaho	83864	Recruiting
Saint Luke's Cancer Institute - Twin Falls	Twin Falls	Idaho	83301	Recruiting
Northwest Community Hospital	Arlington Heights	Illinois	60005	Recruiting
Rush-Copley Medical Center	Aurora	Illinois	60504	Recruiting
Centralia Oncology Clinic	Centralia	Illinois	62801	Recruiting
Northwestern University	Chicago	Illinois	60611	Recruiting
John H Stroger Jr Hospital of Cook County	Chicago	Illinois	60612	Recruiting
Rush MD Anderson Cancer Center	Chicago	Illinois	60612	Active, not recruiting
University of Chicago Comprehensive Cancer Center	Chicago	Illinois	60637	Recruiting
Carle at The Riverfront	Danville	Illinois	61832	Recruiting
Northwestern Medicine Cancer Center Kishwaukee	DeKalb	Illinois	60115	Recruiting
Cancer Care Specialists of Illinois - Decatur	Decatur	Illinois	62526	Recruiting
Decatur Memorial Hospital	Decatur	Illinois	62526	Recruiting
Carle Physician Group-Effingham	Effingham	Illinois	62401	Recruiting
Crossroads Cancer Center	Effingham	Illinois	62401	Recruiting
NorthShore University HealthSystem-Evanston Hospital	Evanston	Illinois	60201	Recruiting
Northwestern Medicine Cancer Center Delnor	Geneva	Illinois	60134	Recruiting
NorthShore University HealthSystem-Glenbrook Hospital	Glenview	Illinois	60026	Recruiting
Northwestern Medicine Glenview Outpatient Center	Glenview	Illinois	60026	Active, not recruiting
Northwestern Medicine Grayslake Outpatient Center	Grayslake	Illinois	60030	Active, not recruiting
Ingalls Memorial Hospital	Harvey	Illinois	60426	Recruiting
NorthShore University HealthSystem-Highland Park Hospital	Highland Park	Illinois	60035	Recruiting
Sudarshan K Sharma MD Limited-Gynecologic Oncology	Hinsdale	Illinois	60521	Active, not recruiting
Northwestern Medicine Lake Forest Hospital	Lake Forest	Illinois	60045	Recruiting
Carle Physician Group-Mattoon/Charleston	Mattoon	Illinois	61938	Recruiting
UC Comprehensive Cancer Center at Silver Cross	New Lenox	Illinois	60451	Recruiting
Carle Cancer Institute Normal	Normal	Illinois	61761	Recruiting
Cancer Care Center of O'Fallon	O'Fallon	Illinois	62269	Recruiting
Northwestern Medicine Orland Park	Orland Park	Illinois	60462	Recruiting
University of Chicago Medicine-Orland Park	Orland Park	Illinois	60462	Recruiting
UW Health Carbone Cancer Center Rockford	Rockford	Illinois	61114	Recruiting
Southern Illinois University School of Medicine	Springfield	Illinois	62702	Recruiting
Springfield Clinic	Springfield	Illinois	62702	Recruiting
Springfield Memorial Hospital	Springfield	Illinois	62781	Recruiting
Carle Cancer Center	Urbana	Illinois	61801	Recruiting
Northwestern Medicine Cancer Center Warrenville	Warrenville	Illinois	60555	Recruiting
Rush-Copley Healthcare Center	Yorkville	Illinois	60560	Recruiting
IU Health North Hospital	Carmel	Indiana	46032	Recruiting
Northwest Cancer Center - Crown Point	Crown Point	Indiana	46307	Recruiting
UChicago Medicine Northwest Indiana	Crown Point	Indiana	46307	Recruiting
Northwest Oncology LLC	Dyer	Indiana	46311	Recruiting
Goshen Center for Cancer Care	Goshen	Indiana	46526	Recruiting
Northwest Cancer Center - Hobart	Hobart	Indiana	46342	Recruiting
Saint Mary Medical Center	Hobart	Indiana	46342	Recruiting
Indiana University/Melvin and Bren Simon Cancer Center	Indianapolis	Indiana	46202	Recruiting
Franciscan Health Indianapolis	Indianapolis	Indiana	46237	Recruiting
Ascension Saint Vincent Indianapolis Hospital	Indianapolis	Indiana	46260	Active, not recruiting
Saint Catherine Hospital	Indianapolis	Indiana	46312	Recruiting
Franciscan Saint Elizabeth Health - Lafayette East	Lafayette	Indiana	47905	Recruiting
Franciscan Health Mooresville	Mooresville	Indiana	46158	Recruiting
The Community Hospital	Munster	Indiana	46321	Recruiting
Women's Diagnostic Center - Munster	Munster	Indiana	46321	Recruiting
Memorial Hospital of South Bend	South Bend	Indiana	46601	Recruiting
Northwest Cancer Center - Valparaiso	Valparaiso	Indiana	46383	Recruiting
Mary Greeley Medical Center	Ames	Iowa	50010	Recruiting
McFarland Clinic - Ames	Ames	Iowa	50010	Recruiting
McFarland Clinic - Boone	Boone	Iowa	50036	Suspended
Heartland Oncology and Hematology LLP	Council Bluffs	Iowa	51503	Suspended
Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ	Council Bluffs	Iowa	51503	Recruiting
McFarland Clinic - Trinity Cancer Center	Fort Dodge	Iowa	50501	Recruiting
University of Iowa/Holden Comprehensive Cancer Center	Iowa City	Iowa	52242	Recruiting
McFarland Clinic - Jefferson	Jefferson	Iowa	50129	Suspended
McFarland Clinic - Marshalltown	Marshalltown	Iowa	50158	Recruiting
Saint Elizabeth Healthcare Edgewood	Edgewood	Kentucky	41017	Recruiting
Baptist Health Lexington	Lexington	Kentucky	40503	Recruiting
Baptist Health Louisville	Louisville	Kentucky	40207	Suspended
LSU Health Baton Rouge-North Clinic	Baton Rouge	Louisiana	70805	Recruiting
Our Lady of the Lake Physician Group	Baton Rouge	Louisiana	70808	Recruiting
Our Lady of the Lake Medical Oncology	Baton Rouge	Louisiana	70817	Recruiting
Ochsner Hematology Oncology North Shore - Covington (West Region)	Covington	Louisiana	70433	Recruiting
West Jefferson Medical Center	Marrero	Louisiana	70072	Recruiting
East Jefferson General Hospital	Metairie	Louisiana	70006	Recruiting
LSU Healthcare Network / Metairie Multi-Specialty Clinic	Metairie	Louisiana	70006	Recruiting
University Medical Center New Orleans	New Orleans	Louisiana	70112	Recruiting
Ochsner Baptist Medical Center	New Orleans	Louisiana	70115	Recruiting
Ochsner Medical Center Jefferson	New Orleans	Louisiana	70121	Recruiting
Harold Alfond Center for Cancer Care	Augusta	Maine	04330	Recruiting
MaineHealth Maine Medical Center- Scarborough	Scarborough	Maine	04074	Recruiting
Greater Baltimore Medical Center	Baltimore	Maryland	21204	Suspended
Sinai Hospital of Baltimore	Baltimore	Maryland	21215	Recruiting
MedStar Franklin Square Medical Center/Weinberg Cancer Institute	Baltimore	Maryland	21237	Recruiting
Johns Hopkins University/Sidney Kimmel Cancer Center	Baltimore	Maryland	21287	Recruiting
Walter Reed National Military Medical Center	Bethesda	Maryland	20889-5600	Recruiting
William E Kahlert Regional Cancer Center/Sinai Hospital	Westminster	Maryland	21157	Recruiting
Baystate Medical Center	Springfield	Massachusetts	01199	Recruiting
University of Michigan Rogel Cancer Center	Ann Arbor	Michigan	48109	Recruiting
Bronson Battle Creek	Battle Creek	Michigan	49017	Recruiting
Trinity Health IHA Medical Group Hematology Oncology - Brighton	Brighton	Michigan	48114	Recruiting
Trinity Health IHA Medical Group Hematology Oncology - Canton	Canton	Michigan	48188	Recruiting
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital	Chelsea	Michigan	48118	Recruiting
Wayne State University/Karmanos Cancer Institute	Detroit	Michigan	48201	Active, not recruiting
Weisberg Cancer Treatment Center	Farmington Hills	Michigan	48334	Active, not recruiting
Corewell Health Farmington Hills Hospital	Farmington Hills	Michigan	48336	Active, not recruiting
Cancer Hematology Centers - Flint	Flint	Michigan	48503	Recruiting
Genesee Hematology Oncology PC	Flint	Michigan	48503	Suspended
Genesys Hurley Cancer Institute	Flint	Michigan	48503	Recruiting
Hurley Medical Center	Flint	Michigan	48503	Recruiting
Corewell Health Grand Rapids Hospitals - Butterworth Hospital	Grand Rapids	Michigan	49503	Recruiting
Trinity Health Grand Rapids Hospital	Grand Rapids	Michigan	49503	Recruiting
Bronson Methodist Hospital	Kalamazoo	Michigan	49007	Recruiting
West Michigan Cancer Center	Kalamazoo	Michigan	49007	Recruiting
Beacon Kalamazoo Cancer Center	Kalamazoo	Michigan	49009	Recruiting
Trinity Health Saint Mary Mercy Livonia Hospital	Livonia	Michigan	48154	Recruiting
Trinity Health Muskegon Hospital	Muskegon	Michigan	49444	Recruiting
Corewell Health Lakeland Hospitals - Niles Hospital	Niles	Michigan	49120	Recruiting
Cancer and Hematology Centers of Western Michigan - Norton Shores	Norton Shores	Michigan	49444	Recruiting
Trinity Health Saint Joseph Mercy Oakland Hospital	Pontiac	Michigan	48341	Recruiting
Corewell Health Reed City Hospital	Reed City	Michigan	49677	Recruiting
Corewell Health William Beaumont University Hospital	Royal Oak	Michigan	48073	Active, not recruiting
MyMichigan Medical Center Saginaw	Saginaw	Michigan	48601	Recruiting
Oncology Hematology Associates of Saginaw Valley PC	Saginaw	Michigan	48604	Suspended
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center	Saint Joseph	Michigan	49085	Recruiting
Corewell Health Lakeland Hospitals - Saint Joseph Hospital	Saint Joseph	Michigan	49085	Recruiting
MyMichigan Medical Center Tawas	Tawas City	Michigan	48764	Recruiting
Munson Medical Center	Traverse City	Michigan	49684	Recruiting
Corewell Health Beaumont Troy Hospital	Troy	Michigan	48085	Active, not recruiting
Saint Mary's Oncology/Hematology Associates of West Branch	West Branch	Michigan	48661	Suspended
University of Michigan Health - West	Wyoming	Michigan	49519	Recruiting
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus	Ypsilanti	Michigan	48197	Recruiting
Mercy Hospital	Coon Rapids	Minnesota	55433	Recruiting
Fairview Southdale Hospital	Edina	Minnesota	55435	Recruiting
Minnesota Oncology Hematology PA-Maplewood	Maplewood	Minnesota	55109	Recruiting
Avera Cancer Institute at Marshall	Marshall	Minnesota	56258	Recruiting
Abbott-Northwestern Hospital	Minneapolis	Minnesota	55407	Recruiting
University of Minnesota/Masonic Cancer Center	Minneapolis	Minnesota	55455	Recruiting
Park Nicollet Clinic - Saint Louis Park	Saint Louis Park	Minnesota	55416	Recruiting
Regions Hospital	Saint Paul	Minnesota	55101	Recruiting
United Hospital	Saint Paul	Minnesota	55102	Recruiting
Minnesota Oncology Hematology PA-Woodbury	Woodbury	Minnesota	55125	Recruiting
MU Health - University Hospital/Ellis Fischel Cancer Center	Columbia	Missouri	65212	Suspended
Phelps Health Delbert Day Cancer Institute	Rolla	Missouri	65401	Recruiting
CoxHealth South Hospital	Springfield	Missouri	65807	Recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Mercy Hospital South	St Louis	Missouri	63128	Recruiting
Mercy Hospital Saint Louis	St Louis	Missouri	63141	Recruiting
Community Hospital of Anaconda	Anaconda	Montana	59711	Recruiting
Billings Clinic Cancer Center	Billings	Montana	59101	Recruiting
Saint Vincent Frontier Cancer Center	Billings	Montana	59102	Recruiting
Intermountain Health West End Clinic	Billings	Montana	59106	Recruiting
Bozeman Health Deaconess Hospital	Bozeman	Montana	59715	Recruiting
Benefis Sletten Cancer Institute	Great Falls	Montana	59405	Recruiting
Logan Health Medical Center	Kalispell	Montana	59901	Recruiting
Saint Patrick Hospital - Community Hospital	Missoula	Montana	59802	Recruiting
Community Medical Center	Missoula	Montana	59804	Recruiting
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC	Omaha	Nebraska	68114	Recruiting
Nebraska Methodist Hospital	Omaha	Nebraska	68114	Recruiting
Alegent Health Bergan Mercy Medical Center	Omaha	Nebraska	68124	Suspended
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
OptumCare Cancer Care at Charleston	Las Vegas	Nevada	89102	Recruiting
Women's Cancer Center of Nevada	Las Vegas	Nevada	89106	Recruiting
OptumCare Cancer Care at Fort Apache	Las Vegas	Nevada	89183	Recruiting
Memorial Sloan Kettering Basking Ridge	Basking Ridge	New Jersey	07920	Recruiting
Cooper Hospital University Medical Center	Camden	New Jersey	08103	Recruiting
Hackensack University Medical Center	Hackensack	New Jersey	07601	Recruiting
Monmouth Medical Center Southern Campus	Lakewood	New Jersey	08701	Recruiting
Saint Barnabas Medical Center	Livingston	New Jersey	07039	Recruiting
Monmouth Medical Center	Long Branch	New Jersey	07740	Recruiting
Memorial Sloan Kettering Monmouth	Middletown	New Jersey	07748	Recruiting
Memorial Sloan Kettering Bergen	Montvale	New Jersey	07645	Recruiting
Virtua Samson Cancer Center	Moorestown	New Jersey	08057	Active, not recruiting
Jersey Shore Medical Center	Neptune City	New Jersey	07753	Recruiting
Rutgers Cancer Institute of New Jersey	New Brunswick	New Jersey	08903	Recruiting
Rutgers New Jersey Medical School	Newark	New Jersey	07101	Recruiting
Riverview Medical Center/Booker Cancer Center	Red Bank	New Jersey	07701	Recruiting
Sidney Kimmel Cancer Center Washington Township	Sewell	New Jersey	08080	Recruiting
Robert Wood Johnson University Hospital Somerset	Somerville	New Jersey	08876	Recruiting
Community Medical Center	Toms River	New Jersey	08755	Recruiting
Virtua Voorhees	Voorhees Township	New Jersey	08043	Active, not recruiting
University of New Mexico Cancer Center	Albuquerque	New Mexico	87106	Recruiting
Presbyterian Kaseman Hospital	Albuquerque	New Mexico	87110	Active, not recruiting
Presbyterian Rust Medical Center/Jorgensen Cancer Center	Rio Rancho	New Mexico	87124	Active, not recruiting
Women's Cancer Care Associates LLC	Albany	New York	12208	Recruiting
Memorial Sloan Kettering Commack	Commack	New York	11725	Recruiting
Memorial Sloan Kettering Westchester	Harrison	New York	10604	Recruiting
NYU Langone Hospital - Long Island	Mineola	New York	11501	Recruiting
Mount Sinai Chelsea	New York	New York	10011	Recruiting
Laura and Isaac Perlmutter Cancer Center at NYU Langone	New York	New York	10016	Recruiting
Mount Sinai Hospital	New York	New York	10029	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
University of Rochester	Rochester	New York	14642	Recruiting
State University of New York Upstate Medical University	Syracuse	New York	13210	Recruiting
Memorial Sloan Kettering Nassau	Uniondale	New York	11553	Recruiting
Wilmot Cancer Institute at Webster	Webster	New York	14580	Recruiting
Duke Cancer Center Cary	Cary	North Carolina	27518	Recruiting
UNC Lineberger Comprehensive Cancer Center	Chapel Hill	North Carolina	27599	Recruiting
Duke University Medical Center	Durham	North Carolina	27710	Recruiting
ECU Health Medical Center	Greenville	North Carolina	27834	Recruiting
Hayworth Cancer Center	High Point	North Carolina	27262	Active, not recruiting
Duke Women's Cancer Care Raleigh	Raleigh	North Carolina	27607	Recruiting
Novant Health New Hanover Regional Medical Center	Wilmington	North Carolina	28401	Recruiting
Wake Forest University Health Sciences	Winston-Salem	North Carolina	27157	Active, not recruiting
Sanford Bismarck Medical Center	Bismarck	North Dakota	58501	Recruiting
Sanford Broadway Medical Center	Fargo	North Dakota	58122	Recruiting
Sanford Roger Maris Cancer Center	Fargo	North Dakota	58122	Recruiting
UHHS-Chagrin Highlands Medical Center	Beachwood	Ohio	44122	Recruiting
Strecker Cancer Center-Belpre	Belpre	Ohio	45714	Recruiting
Aultman Health Foundation	Canton	Ohio	44710	Recruiting
Miami Valley Hospital South	Centerville	Ohio	45459	Recruiting
Geauga Hospital	Chardon	Ohio	44024	Recruiting
Adena Regional Medical Center	Chillicothe	Ohio	45601	Recruiting
Good Samaritan Hospital - Cincinnati	Cincinnati	Ohio	45220	Recruiting
Case Western Reserve University	Cleveland	Ohio	44106	Recruiting
MetroHealth Medical Center	Cleveland	Ohio	44109	Recruiting
Ohio State University Comprehensive Cancer Center	Columbus	Ohio	43210	Recruiting
Mount Carmel East Hospital	Columbus	Ohio	43213	Recruiting
Riverside Methodist Hospital	Columbus	Ohio	43214	Suspended
The Mark H Zangmeister Center	Columbus	Ohio	43219	Recruiting
Miami Valley Hospital	Dayton	Ohio	45409	Recruiting
Miami Valley Hospital North	Dayton	Ohio	45415	Recruiting
Atrium Medical Center-Middletown Regional Hospital	Franklin	Ohio	45005-1066	Recruiting
Miami Valley Cancer Care and Infusion	Greenville	Ohio	45331	Recruiting
Mount Carmel Grove City Hospital	Grove City	Ohio	43123	Recruiting
Fairfield Medical Center	Lancaster	Ohio	43130	Suspended
Saint Rita's Medical Center	Lima	Ohio	45801	Recruiting
Marietta Memorial Hospital	Marietta	Ohio	45750	Recruiting
Memorial Hospital	Marysville	Ohio	43040	Recruiting
UH Seidman Cancer Center at Lake Health Mentor Campus	Mentor	Ohio	44060	Recruiting
Knox Community Hospital	Mount Vernon	Ohio	43050	Recruiting
Licking Memorial Hospital	Newark	Ohio	43055	Recruiting
University Hospitals Parma Medical Center	Parma	Ohio	44129	Recruiting
Mercy Health - Perrysburg Hospital	Perrysburg	Ohio	43551	Recruiting
Southern Ohio Medical Center	Portsmouth	Ohio	45662	Recruiting
Springfield Regional Cancer Center	Springfield	Ohio	45504	Recruiting
Springfield Regional Medical Center	Springfield	Ohio	45504	Recruiting
ProMedica Flower Hospital	Sylvania	Ohio	43560	Recruiting
Mercy Health - Saint Vincent Hospital	Toledo	Ohio	43608	Recruiting
Mercy Health - Saint Anne Hospital	Toledo	Ohio	43623	Recruiting
Upper Valley Medical Center	Troy	Ohio	45373	Recruiting
Saint Ann's Hospital	Westerville	Ohio	43081	Recruiting
UH Seidman Cancer Center at Saint John Medical Center	Westlake	Ohio	44145	Recruiting
Genesis Healthcare System Cancer Care Center	Zanesville	Ohio	43701	Recruiting
University of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma	73104	Recruiting
Mercy Hospital Oklahoma City	Oklahoma City	Oklahoma	73120	Recruiting
Oklahoma Cancer Specialists and Research Institute-Tulsa	Tulsa	Oklahoma	74146	Recruiting
Providence Cancer Institute Clackamas Clinic	Clackamas	Oregon	97015	Suspended
Providence Newberg Medical Center	Newberg	Oregon	97132	Recruiting
Saint Alphonsus Cancer Care Center-Ontario	Ontario	Oregon	97914	Recruiting
Legacy Good Samaritan Hospital and Medical Center	Portland	Oregon	97210	Recruiting
Providence Portland Medical Center	Portland	Oregon	97213	Recruiting
Providence Saint Vincent Medical Center	Portland	Oregon	97225	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Legacy Meridian Park Hospital	Tualatin	Oregon	97062	Recruiting
Lehigh Valley Hospital-Cedar Crest	Allentown	Pennsylvania	18103	Recruiting
Saint Luke's Cancer Center - Allentown	Allentown	Pennsylvania	18104	Recruiting
Saint Luke's University Hospital-Bethlehem Campus	Bethlehem	Pennsylvania	18015	Recruiting
Lehigh Valley Hospital - Muhlenberg	Bethlehem	Pennsylvania	18017	Recruiting
Bryn Mawr Hospital	Bryn Mawr	Pennsylvania	19010	Recruiting
Pocono Medical Center	East Stroudsburg	Pennsylvania	18301	Recruiting
Saint Luke's Hospital-Anderson Campus	Easton	Pennsylvania	18045	Recruiting
Saint Vincent Hospital	Erie	Pennsylvania	16544	Active, not recruiting
Lehigh Valley Hospital-Hazleton	Hazleton	Pennsylvania	18201	Recruiting
Jefferson Hospital	Jefferson Hills	Pennsylvania	15025	Active, not recruiting
Riddle Memorial Hospital	Media	Pennsylvania	19063	Recruiting
Forbes Hospital	Monroeville	Pennsylvania	15146	Active, not recruiting
Paoli Memorial Hospital	Paoli	Pennsylvania	19301	Recruiting
Pennsylvania Hospital	Philadelphia	Pennsylvania	19107	Recruiting
Thomas Jefferson University Hospital	Philadelphia	Pennsylvania	19107	Recruiting
Fox Chase Cancer Center	Philadelphia	Pennsylvania	19111	Recruiting
West Penn Hospital	Pittsburgh	Pennsylvania	15224	Active, not recruiting
Saint Luke's Hospital - Upper Bucks Campus	Quakertown	Pennsylvania	18951	Recruiting
Chester County Hospital	West Chester	Pennsylvania	19380	Recruiting
Wexford Health and Wellness Pavilion	Wexford	Pennsylvania	15090	Active, not recruiting
Asplundh Cancer Pavilion	Willow Grove	Pennsylvania	19090	Recruiting
Lankenau Medical Center	Wynnewood	Pennsylvania	19096	Recruiting
Women and Infants Hospital	Providence	Rhode Island	02905	Recruiting
Smilow Cancer Hospital Care Center - Westerly	Westerly	Rhode Island	02891	Recruiting
Saint Joseph's/Candler - Bluffton Campus	Bluffton	South Carolina	29910	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Recruiting
Avera Cancer Institute-Aberdeen	Aberdeen	South Dakota	57401	Recruiting
Rapid City Regional Hospital	Rapid City	South Dakota	57701	Active, not recruiting
Sanford Cancer Center Oncology Clinic	Sioux Falls	South Dakota	57104	Recruiting
Avera Cancer Institute	Sioux Falls	South Dakota	57105	Recruiting
Sanford USD Medical Center - Sioux Falls	Sioux Falls	South Dakota	57117-5134	Recruiting
The West Clinic - Wolf River	Germantown	Tennessee	38138	Active, not recruiting
Dell Seton Medical Center at The University of Texas	Austin	Texas	78701	Suspended
University of Texas at Austin	Austin	Texas	78712	Suspended
Parkland Memorial Hospital	Dallas	Texas	75235	Recruiting
UT Southwestern/Simmons Cancer Center-Dallas	Dallas	Texas	75390	Recruiting
Tarrant County Hospital District/JPS Health Network	Fort Worth	Texas	76104	Recruiting
UT Southwestern/Simmons Cancer Center-Fort Worth	Fort Worth	Texas	76104	Recruiting
Houston Methodist Hospital	Houston	Texas	77030	Suspended
Memorial Hermann Texas Medical Center	Houston	Texas	77030	Recruiting
Methodist Willowbrook Hospital	Houston	Texas	77070	Suspended
Houston Methodist West Hospital	Houston	Texas	77094	Suspended
Houston Methodist Saint John Hospital	Nassau Bay	Texas	77058	Suspended
UT Southwestern Clinical Center at Richardson/Plano	Richardson	Texas	75080	Recruiting
Houston Methodist Sugar Land Hospital	Sugar Land	Texas	77479	Suspended
Houston Methodist The Woodlands Hospital	The Woodlands	Texas	77385	Suspended
Huntsman Cancer Institute/University of Utah	Salt Lake City	Utah	84112	Recruiting
South Jordan Health Center	South Jordan	Utah	84009	Recruiting
University of Virginia Cancer Center	Charlottesville	Virginia	22908	Recruiting
Henrico Doctor's Hospital	Richmond	Virginia	23229	Recruiting
VCU Massey Cancer Center at Stony Point	Richmond	Virginia	23235	Recruiting
VCU Massey Comprehensive Cancer Center	Richmond	Virginia	23298	Recruiting
Carilion Roanoke Memorial Hospital	Roanoke	Virginia	24033	Recruiting
Swedish Cancer Institute-Edmonds	Edmonds	Washington	98026	Recruiting
Swedish Medical Center-First Hill	Seattle	Washington	98122	Recruiting
Legacy Salmon Creek Hospital	Vancouver	Washington	98686	Recruiting
West Virginia University Charleston Division	Charleston	West Virginia	25304	Recruiting
West Virginia University Healthcare	Morgantown	West Virginia	26506	Recruiting
Marshfield Medical Center-EC Cancer Center	Eau Claire	Wisconsin	54701	Recruiting
Saint Vincent Hospital Cancer Center Green Bay	Green Bay	Wisconsin	54301	Recruiting
Saint Vincent Hospital Cancer Center at Saint Mary's	Green Bay	Wisconsin	54303	Recruiting
Gundersen Lutheran Medical Center	La Crosse	Wisconsin	54601	Recruiting
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center	Madison	Wisconsin	53718	Recruiting
University of Wisconsin Carbone Cancer Center - University Hospital	Madison	Wisconsin	53792	Recruiting
Marshfield Medical Center-Marshfield	Marshfield	Wisconsin	54449	Recruiting
Medical College of Wisconsin	Milwaukee	Wisconsin	53226	Recruiting
Marshfield Medical Center - Minocqua	Minocqua	Wisconsin	54548	Recruiting
ProHealth D N Greenwald Center	Mukwonago	Wisconsin	53149	Recruiting
Cancer Center of Western Wisconsin	New Richmond	Wisconsin	54017	Recruiting
ProHealth Oconomowoc Memorial Hospital	Oconomowoc	Wisconsin	53066	Recruiting
Saint Vincent Hospital Cancer Center at Oconto Falls	Oconto Falls	Wisconsin	54154	Recruiting
Marshfield Medical Center-Rice Lake	Rice Lake	Wisconsin	54868	Recruiting
Saint Vincent Hospital Cancer Center at Sheboygan	Sheboygan	Wisconsin	53081	Recruiting
Sheboygan Physicians Group	Sheboygan	Wisconsin	53081	Recruiting
Marshfield Medical Center-River Region at Stevens Point	Stevens Point	Wisconsin	54482	Recruiting
Saint Vincent Hospital Cancer Center at Sturgeon Bay	Sturgeon Bay	Wisconsin	54235-1495	Recruiting
UW Cancer Center at ProHealth Care	Waukesha	Wisconsin	53188	Recruiting
Marshfield Medical Center - Weston	Weston	Wisconsin	54476	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05256225, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 5, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05256225 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →