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Completed Phase 2 Interventional Results available

Safety, Tolerability, and Efficacy Study of UBX1325 in Patients With Neovascular Age-Related Macular Degeneration (ENVISION)

ClinicalTrials.gov ID: NCT05275205

Public ClinicalTrials.gov record NCT05275205. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:03 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Safety, Tolerability, and Evidence of Activity of a Repeat Intravitreal Injection of UBX1325 in Patients With Neovascular Age-Related Macular Degeneration (Wet AMD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is intended to assess safety, tolerability and biological activity of a repeat IVT injection of UBX1325 in patients with wet AMD.

Study identification

NCT ID
NCT05275205
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Unity Biotechnology, Inc.
Industry
Enrollment
51 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 1, 2022
Primary completion
Feb 14, 2023
Completion
Jul 24, 2023
Last update posted
Aug 6, 2024

2022 – 2023

United States locations

U.S. sites
14
U.S. states
9
U.S. cities
14
Facility City State ZIP Site status
Retina-Vitreous Associates Medical Group Beverly Hills California 90211
Salehi Retina Institute Huntington Beach California 92647
Advanced Vision Research Institute Longmont Colorado 80503
Rand Eye Institute Deerfield Beach Florida 33064
Retina Vitreous Associates of Florida St. Petersburg Florida 33711
University Retina and Macula Associates Lemont Illinois 60439
Illinois Eye Center Peoria Illinois 61615
Midwest Eye Carmel Indiana 46290
Mayo Clinic-Rochester Rochester Minnesota 55905
Sierra Eye Associates Reno Nevada 89502
EyeHealth Northwest Portland Oregon 97225
Retina Research Institution of Texas Abilene Texas 79606
Valley Retina Institute McAllen Texas 78503
Austin Retina Associates Round Rock Texas 78681

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05275205, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 6, 2024 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05275205 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →