Three Intermediate Expanded Access Protocols (EAP) CNMAu8.EAP01, CNMAu8.EAP02, and CNMAu8.EAP06 for ALS
Public ClinicalTrials.gov record NCT05281484. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Three Intermediate Expanded Access Protocols for Amyotrophic Lateral Sclerosis With CNM-Au8. CNMAu8.EAP01, CNMAu8.EAP02, and CNMAu8.EAP06
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of the intermediate expanded access protocol is to provide access to the investigational product, CNM-Au8, to up to 300 people living with ALS (pALS). No formal clinical hypotheses are being evaluated with concurrent controls. Secondary objectives include assessment of the safety of CNM-Au8 treatment in pALS. Safety will be assessed through the frequency of serious adverse events (SAEs), treatment-emergent adverse events (TEAEs) assessed as 'severe', discontinuations due to TEAEs, and laboratory abnormalities assessed as clinically significant during routine clinical monitoring (as applicable).
Study identification
- NCT ID
- NCT05281484
- Recruitment status
- Available
- Study type
- Expanded access
- Phase
- Not listed
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Aug 23, 2026
United States locations
- U.S. sites
- 16
- U.S. states
- 14
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute (Enrollment is full, not recruiting) | Phoenix | Arizona | 85013 | Available |
| UC Irvine (Enrollment is full, not recruiting) | Orange | California | 92868 | Available |
| Sutter Health (Enrollment is full, not recruiting) | San Francisco | California | 94107 | Available |
| Hospital for Special Care (Enrollment is full, not recruiting) | New Britain | Connecticut | 06053 | Available |
| Nova Southeastern University (Enrollment is full, not recruiting) | Davie | Florida | 33314 | Available |
| Northwestern (Enrollment is full, not recruiting) | Chicago | Illinois | 60611 | Available |
| University of Kansas (Enrollment is full, not recruiting) | Fairway | Kansas | 66205 | Available |
| Massachusetts General Hospital (Enrollment is full, not recruiting) | Boston | Massachusetts | 02114 | Available |
| Henry Ford Health Systems (Enrollment is full, not recruiting) | Detroit | Michigan | 48322 | Available |
| University of Nebraska Medical Center (Enrollment is full, not recruiting) | Omaha | Nebraska | 68198 | Available |
| DUKE University Medical Center | Durham | North Carolina | 27705 | Available |
| Providence Health (Enrollment is full, not recruiting) | Portland | Oregon | 97225 | Available |
| Penn State Health (Enrollment is full, not recruiting) | Hershey | Pennsylvania | 17033 | Available |
| Jefferson Hospital (Enrollment is full, not recruiting) | Philadelphia | Pennsylvania | 19107 | Available |
| Texas Neurology (Enrollment is full, not recruiting) | Dallas | Texas | 75206 | Available |
| University of Washington (Enrollment is full, not recruiting) | Seattle | Washington | 98195 | Available |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05281484, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 23, 2026 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05281484 live on ClinicalTrials.gov.