Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Older Adults
Public ClinicalTrials.gov record NCT05297578. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Observer-Blind, Dose-Finding, Controlled Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Healthy Adults 65 Years and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of the study is to evaluate the safety and tolerability of a single injection of VAX-24 at 3 dose levels compared to Prevnar 20™ (PCV20) in adults 65 years of age and older.
Study identification
- NCT ID
- NCT05297578
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 207 participants
Conditions and interventions
Conditions
Interventions
- 24-Valent Pneumococcal Conjugate Vaccine Biological
- Pneumococcal 20-valent Conjugate Vaccine Biological
Biological
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 15, 2022 (Actual)
- Primary completion
- Feb 15, 2023 (Actual)
- Completion
- Feb 15, 2023 (Actual)
- Last update posted
- Oct 9, 2024
2022 – 2023
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accel Research Sites-Birmingham Clinical Research Unit | Birmingham | Alabama | 35216 | — |
| Accel Research Sites - DeLand Clinical Research Unit | DeLand | Florida | 32720 | — |
| CenExel RCA | Hollywood | Florida | 33024 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Meridian Clinical Research | Savannah | Georgia | 31406 | — |
| Pivotal Research Solutions | Stonecrest | Georgia | 30038 | — |
| Healthcare Research Network II, LLC | Flossmoor | Illinois | 60422 | — |
| AMR Newton, formerly Heartland Research Associates | Newton | Kansas | 67114 | — |
| AMR Wichita West | Wichita | Kansas | 67205 | — |
| AMR New Orleans | New Orleans | Louisiana | 70119 | — |
| Healthcare Research Network | Hazelwood | Missouri | 63042 | — |
| Meridian Clinical Research | Omaha | Nebraska | 68134 | — |
| Accellacare of Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| Meridian Clinical Research | Cincinnati | Ohio | 45219 | — |
| Accellacare of Charleston | Mt. Pleasant | South Carolina | 29464 | — |
| Coastal Carolina Research | North Charleston | South Carolina | 29405 | — |
| Clinical Trials of Texas, LLC | San Antonio | Texas | 78229 | — |
| CenExel JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
| Velocity Clinical Research, Salt Lake City | West Jordan | Utah | 84088 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05297578, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 9, 2024 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05297578 live on ClinicalTrials.gov.