An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
Public ClinicalTrials.gov record NCT05300724. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Prospective, Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter prospective study in participants with intermediate age-related macular degeneration (iAMD). One primary objective of this study is to assess iAMD disease progression, by the timeline and rates of conversion for high-risk iAMD at baseline to more advanced atrophic AMD stages. The other primary objective of this observational study is to assess the feasibility of measuring the rate of photoreceptor loss as a potential clinical endpoint. The study will consist of an observation period of approximately 3 years (\~144 weeks) for participants.
Study identification
- NCT ID
- NCT05300724
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 400 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 94 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 27, 2022 (Actual)
- Primary completion
- Jun 30, 2027 (Estimated)
- Completion
- Jun 30, 2027 (Estimated)
- Last update posted
- Sep 16, 2026
2022 – 2027
United States locations
- U.S. sites
- 46
- U.S. states
- 27
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Partners of Northwest Arkansas, PLLC | Springdale | Arkansas | 72764 | — |
| The Retina Partners | Encino | California | 91436-2018 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Consultants, San Diego | Poway | California | 92064 | — |
| UC Davis Eye Center | Sacramento | California | 95817 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95841-2013 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Southwest Retina Consultants | Durango | Colorado | 81303 | — |
| Eye Care Center of Northern Colorado PC | Longmont | Colorado | 80503 | — |
| Advanced Research | Coral Springs | Florida | 33067 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| University Retina and Macula Associates, PC | Oak Forest | Illinois | 60452 | — |
| Raj K. Maturi, MD PC | Indianapolis | Indiana | 46290 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Cumberland Valley Retina Consultants PC | Hagerstown | Maryland | 21740 | — |
| New England Retina Consultants | Springfield | Massachusetts | 01107 | — |
| Foundation for Vision Research | Grand Rapids | Michigan | 49546 | — |
| Deep Blue Retina Clinical Research | Southaven | Mississippi | 38671 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Vitreous Retina Macula Consultants of New York | New York | New York | 10022 | — |
| Ophthalmic Consultants of Long Island | Rockville Centre | New York | 11570 | — |
| Duke Eye Center | Durham | North Carolina | 27705 | — |
| Cleveland Clinic Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| Retina Vitreous Center | Edmond | Oklahoma | 73013 | — |
| EyeHealth Northwest | Portland | Oregon | 97224 | — |
| Casey Eye Institute - OHSU | Portland | Oregon | 97239 | — |
| Erie Retinal Surgery | Erie | Pennsylvania | 16507 | — |
| Scheie Eye Institute | Philadelphia | Pennsylvania | 19104 | — |
| Palmetto Retina Center, LLC | West Columbia | South Carolina | 29169 | — |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | — |
| W Texas Retina Consultants PA | Abilene | Texas | 79606 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Retina Specialists | DeSoto | Texas | 75115 | — |
| San Antonio Eye Center | San Antonio | Texas | 78215 | — |
| Rocky Mountain Retina | Salt Lake City | Utah | 84107 | — |
| Wagner Kapoor Institute | Norfolk | Virginia | 23502 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53705-2275 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05300724, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 16, 2026 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05300724 live on ClinicalTrials.gov.