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Completed Phase 3 Interventional Results available

A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19

ClinicalTrials.gov ID: NCT05305547

Public ClinicalTrials.gov record NCT05305547. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 2, 2026, 11:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-Blind, 24-Week Study of the Clinical and Antiviral Effect of S-217622 Compared With Placebo in Non-Hospitalized Participants With COVID-19

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main aim of this study is to evaluate the efficacy of S-217622 versus placebo among outpatient adults with mild and moderate COVID-19 starting intervention within 3 days of symptom onset.

Study identification

NCT ID
NCT05305547
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Shionogi
Industry
Enrollment
2,093 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 3, 2022 (Actual)
Primary completion
Jan 7, 2024 (Actual)
Completion
May 24, 2024 (Actual)
Last update posted
Aug 20, 2026

2022 – 2024

United States locations

U.S. sites
53
U.S. states
22
U.S. cities
46
Facility City State ZIP Site status
Lakeview Clinical Research Guntersville Alabama 35976 —
Voyage Medical Services Tempe Arizona 85282 —
Novak Clinical Research Tucson Arizona 85741 —
Hope Clinical Research Canoga Park California 91303 —
Carbon Health Culver City California 91606 —
NICR Garden Grove California 92866 —
Ark Clinical Research (PARENT) Long Beach California 94110 —
UCSD Antiviral Research Center San Diego California 92103 —
University of California San Francisco (PARENT) San Francisco California 94110 —
Clinical Trials Management Services, 223 E. Thousand Oaks Blvd. Thousand Oaks California 91360 —
Lundquist Institute for BMI, UCLA Medical Center Torrance California 90502 —
University of Colorado Anschutz Medical Campus Aurora Colorado 80045 —
Whitman-Walker Health Washington D.C. District of Columbia 20005 —
University of Florida Clinical & Translational Science Institute Gainesville Florida 32610 —
Universal Medical and Research Center Miami Florida 33134 —
CCR Medical Center, Suite 201 Miami Florida 33144 —
Miami Clinical Research Miami Florida 33155 —
Vista Health Research, LLC Miami Florida 33176 —
Quantum Clinical Trials, 333 Arthur Godfrey Road, Suite 202, suite 208 Miami Beach Florida 33140 —
Quality Research of South Florida Miami Lakes Florida 33016 —
Accel Research Sites Network, Ormond Clinical Research Unit, 77 West Granada Boulevard Ormond Beach Florida 32174 —
Clinical Research Center of Florida, 550 SW 3rd St.,, Suite #305 Pompano Beach Florida 33060 —
Invictus Clinical Research Group, LLC Pompano Beach Florida 33073 —
Santos Research Center, CORP Tampa Florida 33615 —
Masters of Clinical Research Augusta Georgia 30909 —
Leavitt Clinical Research Idaho Falls Idaho 83404 —
Research Network America Berwyn Illinois 60402 —
Rush University Infectious Diseases Chicago Illinois 89109 —
Tandem Clinical Research Marrero Louisiana 70072 —
The Johns Hopkins Hospital Baltimore Maryland 21287 —
Infusion Associates Grand Rapids Michigan 49525 —
Revival Research Institute LLC Troy Michigan 48312 —
Las Vegas Medical Research Las Vegas Nevada 89113 —
AB Clinical Trials Las Vegas Nevada 89119 —
Renal Medicine Associates Albuquerque New Mexico 87901 —
Columbia University Irving Medical Center Division of Infectious Diseases New York New York 10032-3722 —
NY Blood Center Project ACHIEVE New York New York 10065 —
University of Rochester Medical Center Rochester New York 14542 —
Lapis Clinical Research - North State Denver North Carolina 28037 —
Burke Primary Care Morgantown North Carolina 28655 —
Progressive Medicine of the Triad, LLC Winston-Salem North Carolina 27103 —
Ohio State University College of Medicine Columbus Ohio 43201 —
Infectious Disease Clinical Trials Unit-University of Pennsylvania Health System Philadelphia Pennsylvania 19104 —
UPMC Eye Center - Eye and Ear Institute Pittsburgh Pennsylvania 15213 —
Vanderbilt Health-One Hundred Oaks Nashville Tennessee 37204 —
Central Texas Medical Research Austin Texas 78705 —
Care United Research, 375 North FM 548, suite 100 Forney Texas 75126 —
Valley Institute of Research Fort Worth Texas 76164 —
Trio Clinical Trials, LLC. Houston Texas 77008 —
Accurate Clinical Management, LLC Houston Texas 77065 —
Sun Research Institute, LLC San Antonio Texas 78215 —
Progressive Clinical Research Bountiful Utah 84010 —
Clinical Research Partners LLC Richmond Virginia 23226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 143 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05305547, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 20, 2026 · Synced Oct 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05305547 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →