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Completed Phase 1 Interventional

CLN-418 Study on Subjects With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT05306444

Public ClinicalTrials.gov record NCT05306444. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 1, 2026, 7:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CLN-418 in Subjects With Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Study to evaluate the safety and tolerability of the study drug CLN-418, to determine the maximum tolerated dose and/or recommended Phase 2 study dose of CLN-418.

Study identification

NCT ID
NCT05306444
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Harbour BioMed US, Inc.
Industry
Enrollment
48 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 12, 2022 (Actual)
Primary completion
Aug 28, 2024 (Actual)
Completion
Sep 10, 2024 (Actual)
Last update posted
Apr 25, 2025

2022 – 2024

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
USC Norris Comprehensive Cancer Center Los Angeles California 90033 —
Florida Cancer Specialists Sarasota Florida 34232 —
Carolina BioOncology Institute - Cancer Research Centre Huntersville North Carolina 28078 —
MD Anderson Houston Texas 77030 —
NEXT Oncology Irving Texas 75039 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05306444, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 25, 2025 · Synced Oct 1, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05306444 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →