A Study of Seltorexant in Participants With Probable Alzheimer's Disease
Public ClinicalTrials.gov record NCT05307692. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Investigate the Safety, Tolerability, and Clinical Efficacy of Seltorexant (JNJ-42847922) on Behavioral and Psychological Symptoms of Dementia in Patients With Probable Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to investigate the effect of seltorexant versus placebo on the sum of Agitation and Aggression domain scores (A plus A) of the Neuropsychiatric Inventory-Clinician rating (NPI-C) in participants with probable Alzheimer's Disease (AD) with clinically significant agitation/aggression.
Study identification
- NCT ID
- NCT05307692
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 88 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 19, 2022 (Actual)
- Primary completion
- Nov 10, 2023 (Actual)
- Completion
- Nov 10, 2023 (Actual)
- Last update posted
- Apr 27, 2025
2022 – 2023
United States locations
- U.S. sites
- 25
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Advancement Center of Arizona | Tempe | Arizona | 85283 | — |
| Sunwise Clinical Research | Lafayette | California | 94549 | — |
| Luminous Clinical Research | Homestead | Florida | 33030 | — |
| Global Medical Institutes | Miami | Florida | 33125 | — |
| Office of Emilio Mantero-Atienza, MD | Miami | Florida | 33135 | — |
| Allied Biomedical Research Institute (ABRI), Inc | Miami | Florida | 33155-4630 | — |
| Quantix Research | Miami | Florida | 33155 | — |
| Entrust Clinical Research | Miami | Florida | 33156 | — |
| Florida International Research Center (FIRC) | Miami | Florida | 33173 | — |
| P&S Research, LLC | Miami | Florida | 33175 | — |
| IMIC Inc | Miami | Florida | 33176 | — |
| Biovision Medical | Miami | Florida | 33184 | — |
| South Florida Research Center Inc. | Miami Springs | Florida | 33166 | — |
| Intercoastal Medical Group | Sarasota | Florida | 34239 | — |
| Accel Clinical Research | Seminole | Florida | 33777 | — |
| Sonar Clinical Research | Atlanta | Georgia | 30315 | — |
| NeuroTrials Research Inc | Atlanta | Georgia | 30328 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Gill Neuroscience | Cypress | Texas | 77429 | — |
| Wasatch Clinical Research | Salt Lake City | Utah | 84107 | — |
| Memory Clinic Inc | Bennington | Vermont | 05201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05307692, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2025 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05307692 live on ClinicalTrials.gov.