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Recruiting Not applicable Interventional

Cardiac Outcomes With Near-Complete Estrogen Deprivation

ClinicalTrials.gov ID: NCT05309655

Public ClinicalTrials.gov record NCT05309655. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The Cardiac Outcomes With Near-Complete Estrogen Deprivation (CROWN) Study

Study identification

NCT ID
NCT05309655
Recruitment status
Recruiting
Study type
Interventional
Phase
Not applicable
Lead sponsor
Duke University
Other
Enrollment
90 participants

Conditions and interventions

Interventions

  • Adenosine Stress Cardiac Magnetic Resonance Imaging Drug
  • Electrocardiogram Diagnostic Test
  • Computed Tomography Angiogram Diagnostic Test
  • Laboratory Testing Other
  • Quality of Life Survey Behavioral

Drug · Diagnostic Test · Other + 1 more

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 1, 2022
Primary completion
Apr 30, 2028
Completion
Nov 30, 2028
Last update posted
Mar 15, 2026

2022 – 2028

United States locations

U.S. sites
3
U.S. states
2
U.S. cities
3
Facility City State ZIP Site status
Duke Cancer Center Durham North Carolina 27710 Recruiting
Wake Forest Baptist Comprehensive Cancer Center Winston-Salem North Carolina 27157 Recruiting
Virginia Commonwealth University Massey Cancer Center Richmond Virginia 23298 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05309655, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 15, 2026 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05309655 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →