Ultrafiltration Versus IV Diuretics in Worsening Heart Failure
Public ClinicalTrials.gov record NCT05318105. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Controlled Study to Evaluate the Safety and Effectiveness of the Aquadex System in Patients With Heart Failure and Fluid Overload
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The REVERSE-HF study is a randomized controlled trial to evaluate clinical outcomes of adjustable ultrafiltration with the Aquadex System as compared to adjustable IV loop diuretics in patients with worsening heart failure (HF) and fluid overload.
Study identification
- NCT ID
- NCT05318105
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 167 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 28, 2022 (Actual)
- Primary completion
- Oct 6, 2025 (Actual)
- Completion
- Apr 7, 2026 (Actual)
- Last update posted
- Jun 25, 2026
2022 – 2026
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Health | Tucson | Arizona | 85721 | — |
| MemorialCare, Long Beach Medical Center | Long Beach | California | 90806 | — |
| Sharp Memorial Hospital, San Diego Cardiac Center | San Diego | California | 92123 | — |
| BayCare Medical Group, Morton Plant | Clearwater | Florida | 33756 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Henry Ford Health | Detroit | Michigan | 48202 | — |
| Mount Sinai Morningside | New York | New York | 10025 | — |
| The Mount Sinai Hospital | New York | New York | 10029 | — |
| Northwell Health | New York | New York | 10075 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| The Ohio State University | Columbus | Ohio | 43215 | — |
| Abington Jefferson Health | Abington | Pennsylvania | 19001 | — |
| Jackson Madison County General Hospital | Jackson | Tennessee | 38301 | — |
| Baylor Scott & White Research Institute | Dallas | Texas | 75207 | — |
| Sentara Norfolk General Heart Hospital | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05318105, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2026 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05318105 live on ClinicalTrials.gov.