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Recruiting Phase 1Phase 2 Interventional

LYL273 for Patients With Relapsed or Refractory mCRC

ClinicalTrials.gov ID: NCT05319314

Public ClinicalTrials.gov record NCT05319314. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 12:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Multicenter Study Evaluating the Safety and Efficacy of LYL273 in Patients With Relapsed or Refractory Metastatic Colorectal Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 1/2 open-label, multicenter study evaluating the safety and efficacy of LYL273 in participants with relapsed or refractory metastatic colorectal cancer.

Study identification

NCT ID
NCT05319314
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Lyell Immunopharma, Inc.
Industry
Enrollment
155 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 1, 2022 (Actual)
Primary completion
Jun 2028 (Estimated)
Completion
Jun 2032 (Estimated)
Last update posted
Oct 23, 2026

2022 – 2032

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
City of Hope Comprehensive Cancer Center Duarte California 91010 Recruiting
University of California San Francisco Medical Center San Francisco California 94143 Recruiting
University of Colorado Hospital - Anschutz Cancer Pavilion Aurora Colorado 80045 Recruiting
Dana-Farber Cancer Institute Boston Massachusetts 02215-5418 Recruiting
SCRI Oncology Partners and Tristar Centennial Hospital Nashville Tennessee 37203 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05319314, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 23, 2026 · Synced Oct 29, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05319314 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →