A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
Public ClinicalTrials.gov record NCT05321069. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double Blind, Randomized, Placebo-controlled Trial Evaluating the Efficacy and Safety of BI 1015550 Over at Least 52 Weeks in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is open to adults with a lung disease called Idiopathic Pulmonary Fibrosis (IPF). People can join the study if they are 40 years or older. If they already take nintedanib or pirfenidone for their IPF, they can continue treatment throughout the study. The purpose of this study is to find out whether a medicine called BI 1015550 helps people with IPF. Participants are put into 3 groups randomly, which means by chance. Participants in 2 groups take different doses of BI 1015550 as tablets twice a day. Participants in the placebo group take placebo tablets twice a day. Placebo tablets look like BI 1015550 tablets but do not contain any medicine. Participants are in the study for up to two and a half years. During the first year, they visit the study site 10 times. Afterwards, they visit the study site every 3 months. The doctors regularly test participants' lung function. The results of the lung function tests are compared between the groups. The doctors also regularly check participants' health and take note of any unwanted effects.
Study identification
- NCT ID
- NCT05321069
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,177 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 6, 2022 (Actual)
- Primary completion
- Aug 16, 2024 (Actual)
- Completion
- Dec 17, 2024 (Actual)
- Last update posted
- Oct 20, 2025
2022 – 2024
United States locations
- U.S. sites
- 56
- U.S. states
- 30
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Christiana Hospital | Newark | Delaware | 19713 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| St. Francis Medical Institute | Clearwater | Florida | 33765 | — |
| University of Florida Health Shands Hospital | Gainesville | Florida | 32610 | — |
| Clinical Research Specialists LLC | Kissimmee | Florida | 34746 | — |
| Advanced Pulmonary Research Institute | Loxahatchee Groves | Florida | 33470 | — |
| Destin Pulmonary Critical Care | Santa Rosa Beach | Florida | 32459 | — |
| Piedmont Healthcare-Atlanta-57055 | Atlanta | Georgia | 30309 | — |
| Evanston Hospital Pulmonary Clinic | Evanston | Illinois | 60201 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Louisville Pulmonary Care | Louisville | Kentucky | 40207 | — |
| Tulane University Hospital and Clinic | New Orleans | Louisiana | 70112 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| St. Elizabeth's Medical Center | Boston | Massachusetts | 02135 | — |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109-5314 | — |
| Beaumont Health | Royal Oak | Michigan | 48073 | — |
| Minnesota Lung Center and Sleep Institute | Edina | Minnesota | 55435 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic, Rochester | Rochester | Minnesota | 55905 | — |
| The Lung Research Center, LLC | Chesterfield | Missouri | 63017 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Creighton University | Omaha | Nebraska | 68124 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Northern Westchester Hospital | Mount Kisco | New York | 10549 | — |
| Columbia University Medical Center-New York Presbyterian Hospital | New York | New York | 10032 | — |
| Weill Cornell Medicine-New York-59955 | New York | New York | 10065 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Southeastern Research Center-Winston-Salem-61365 | Winston-Salem | North Carolina | 27103 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| The Oregon Clinic | Portland | Oregon | 97220 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Jefferson Health Honickman Center | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Lowcountry Lung and Critical Care | Charleston | South Carolina | 29406 | — |
| Clinical Trials Center of Middle Tennessee, LLC | Franklin | Tennessee | 37067 | — |
| Vanderbilt University Medical Center - Vanderbilt Lung Institute at 100 Oaks | Nashville | Tennessee | 37204 | — |
| Premier Pulmonary Critical Care and Sleep Medicine | Denison | Texas | 75020 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| UT Health San Antonio | San Antonio | Texas | 78229 | — |
| University of Utah Health Sciences Center | Salt Lake City | Utah | 84108 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 278 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05321069, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 20, 2025 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05321069 live on ClinicalTrials.gov.