LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Public ClinicalTrials.gov record NCT05321420. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Double-blind, Four-Arm Active and Placebo-controlled Dose-Finding Trial to Evaluate the Efficacy, Tolerability, Safety and Dose Response of LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study a randomized, double-blind, four arm study to evaluate the safety and efficacy of LYT-100 compared to pirfenidone or placebo in adults with Idiopathic Pulmonary Fibrosis.
Study identification
- NCT ID
- NCT05321420
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 22, 2022 (Actual)
- Primary completion
- Oct 15, 2024 (Actual)
- Completion
- Dec 31, 2025 (Estimated)
- Last update posted
- Oct 16, 2025
2022 – 2025
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35294 | — |
| Science 37 | Los Angeles | California | 90230 | — |
| NewportNativeMD, Inc. | Newport Beach | California | 92663 | — |
| Paradigm Clinical Research Centers, Inc. | Redding | California | 96001 | — |
| Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center | Torrance | California | 90502 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | — |
| Accel Research Sites Network | DeLand | Florida | 32720 | — |
| Harmony Medical Research Institute, Inc | Hialeah | Florida | 33016 | — |
| Piedmont Healthcare, Inc. | Atlanta | Georgia | 30309 | — |
| Clinical Research Investments | Decatur | Georgia | 30030 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Pulmonix | Greensboro | North Carolina | 27403 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Temple University | Philadelphia | Pennsylvania | 19140 | — |
| Clinical Trials Center of Middle Tennessee | Franklin | Tennessee | 37067 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37204 | — |
| Baylor Scott & White Research Institute | Dallas | Texas | 75204 | — |
| Renovatio Clinical - The Woodlands Research Center | The Woodlands | Texas | 77380 | — |
| Pulmonary Associates of Richmond | Richmond | Virginia | 23230 | — |
| TPMG Clinical Research | Williamsburg | Virginia | 23188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 81 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05321420, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2025 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05321420 live on ClinicalTrials.gov.