Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis
Public ClinicalTrials.gov record NCT05327127. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
Study to Evaluate the Efficacy and Safety of Combination Therapy of K-877-ER and CSG452 in Participants With Noncirrhotic Nonalcoholic Steatohepatitis (NASH) With Liver Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A study to investigate the use of combination therapy with two investigational products for the treatment of adult patients with Nonalcoholic steatohepatitis (NASH).
Study identification
- NCT ID
- NCT05327127
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 228 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 14, 2022 (Actual)
- Primary completion
- May 20, 2026 (Actual)
- Completion
- Jun 3, 2026 (Actual)
- Last update posted
- Jun 26, 2026
2022 – 2026
United States locations
- U.S. sites
- 37
- U.S. states
- 18
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Adobe Clinical Research, LLC | Tucson | Arizona | 85712 | — |
| Arizona Liver Health | Tucson | Arizona | 85712 | — |
| Arcare Center for Clinical Research | Little Rock | Arkansas | 72205 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| United Clinical Research Institute | Los Alamitos | California | 90720 | — |
| Velocity Clinical Research | Los Angeles | California | 90057 | — |
| Alliance Clinical Research | Poway | California | 92064 | — |
| Nature Coast Clinical Research, LLC | Inverness | Florida | 34452 | — |
| ENCORE Borland Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| Miami Clinical Research | Miami | Florida | 33155 | — |
| Ocala GI Research | Ocala | Florida | 34471 | — |
| Sensible Healthcare Clinical Research, LLC | Ocoee | Florida | 34761 | — |
| Centricity Research | Columbus | Georgia | 31904 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Iowa Digestive Disease Center | Clive | Iowa | 50325 | — |
| Tandem Clinical Research, LLC | Marrero | Louisiana | 70072 | — |
| Mid-Atlantic GI Research, LLC | Greenbelt | Maryland | 20770 | — |
| Boston Medical Center Boston University Chobanian & Avedisian School of Medicine | Boston | Massachusetts | 02118 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| GI Alliance Research | Flowood | Mississippi | 39232 | — |
| GI Associates Research, LLC | Columbia | Missouri | 65201 | — |
| Jefferson City Medical Group | Jefferson City | Missouri | 65109 | — |
| Lucas Research, Inc. | Morehead City | North Carolina | 28557 | — |
| DSI Research Northridge, LLC | Dayton | Ohio | 45414 | — |
| Penn State Health/Penn State College of Medicine | Hershey | Pennsylvania | 17033 | — |
| GI Alliance Research | Cedar Park | Texas | 78613 | — |
| GI Alliance Research | Dallas | Texas | 75246 | — |
| GI Alliance Research | Garland | Texas | 75044 | — |
| GLRI McAllen Research | Pharr | Texas | 78577 | — |
| Northeast Clinical Rsearch of San Antonio | San Antonio | Texas | 78233 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Impact Research Institute | Waco | Texas | 76710 | — |
| Digestive Health Research of Central Texas, LLC | Waco | Texas | 76712 | — |
| North Richmond Health Research | Richmond | Virginia | 23229 | — |
| GI Select Health Research | Richmond | Virginia | 23236 | — |
| Centricity | Suffolk | Virginia | 23435 | — |
| Liver Institute Northwest | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05327127, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 26, 2026 · Synced Nov 4, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05327127 live on ClinicalTrials.gov.