Open-Label Extension of the PTI-125-04 Study in Mild-to-Moderate Alzheimer's Disease
Public ClinicalTrials.gov record NCT05352763. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Extension of the PTI-125-04 Study Evaluating the Safety and Long-Term Treatment of Simufilam in Mild-to-Moderate Alzheimer's Disease Patients
Study identification
- NCT ID
- NCT05352763
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Cassava Sciences, Inc.
- Industry
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Interventions
- simufilam Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2022
- Primary completion
- Dec 30, 2024
- Completion
- Dec 30, 2024
- Last update posted
- Aug 14, 2025
2022 – 2024
United States locations
- U.S. sites
- 9
- U.S. states
- 7
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cognitive Clinical Trials | Gilbert | Arizona | 85296 | — |
| Valley Research Center, Inc. | Imperial | California | 92251 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| IMIC Research | Palmetto Bay | Florida | 33157 | — |
| Cognitive Clinical Trials | Papillion | Nebraska | 68046 | — |
| Advanced Memory Research Institute of NJ | Toms River | New Jersey | 08755 | — |
| the Ohio State University | Columbus | Ohio | 43221 | — |
| Senior Adults Specialty Research | Austin | Texas | 78757 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05352763, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 14, 2025 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05352763 live on ClinicalTrials.gov.