A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD
Public ClinicalTrials.gov record NCT05357989. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 6-month Prospective, Randomized, Double-blind, Placebo-controlled Clinical Trial Investigating the Efficacy, Safety, and Tolerability of Two Different Doses of Buntanetap or Placebo in Patients With Early Parkinson's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to measure safety and efficacy of buntanetap/posiphen capsules compared with placebo capsules in participants with early PD. Study details include: * The study duration will be up to 7-8 months. * The double-blind treatment duration will be up to 6 months. * There will be 5 in-clinic visits and 7 phone calls
Study identification
- NCT ID
- NCT05357989
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 523 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2, 2022
- Primary completion
- Dec 3, 2023
- Completion
- Dec 3, 2023
- Last update posted
- Mar 2, 2025
2022 – 2023
United States locations
- U.S. sites
- 43
- U.S. states
- 22
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham (UAB)- The Kirklin Clinic | Birmingham | Alabama | 35233-2110 | — |
| Banner Sun Health Research Institute - Cleo Roberts Center for Clinical Research | Sun City | Arizona | 85351-3020 | — |
| Parkinson's & Movement Disorder Institue (PMDI) - Orange County Office | Fountain Valley | California | 92708 | — |
| UCSF Medical Center - Parkinson's Disease and Movement Disorders Clinic | San Francisco | California | 94143-2202 | — |
| Rocky Mountain Movement Disorder Center | Englewood | Colorado | 80113 | — |
| Ki Health Partners LLC D/B/A New England Institute for Clinical Research | Stamford | Connecticut | 06824 | — |
| Visionary Investigators Network | Aventura | Florida | 33180 | — |
| Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton | Florida | 33486-2359 | — |
| The Neurology Institute - Coral Springs | Coral Springs | Florida | 33067-4640 | — |
| Arrow Clinical trial | Daytona Beach | Florida | 32114 | — |
| Accel Research Sites - DeLand Clinical Research Unit | DeLand | Florida | 32720 | — |
| Coral Clinic Reserach LLC | Homestead | Florida | 33032 | — |
| Homestead Associates in Research, Inc | Miami | Florida | 33032 | — |
| Visionary Investigators Networks | Miami | Florida | 33133 | — |
| Medical Professional Clinical Research Center, INC | Miami | Florida | 33165 | — |
| Reliant Medical Research | Miami | Florida | 33165 | — |
| Ezy Medical Research Co. | Miami | Florida | 33175 | — |
| Visionary Investigators Network | Miami | Florida | 33176 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Visionary Investigators Network | Pembroke Pines | Florida | 33026 | — |
| Parkinsons Disease Treatment Center | Port Charlotte | Florida | 33952-6705 | — |
| University of South Florida (USF) - University of South Florida College of Medicine- Parkinson's Disease and Movement Disorders Center | Tampa | Florida | 33613-4808 | — |
| ClinCloud, LLC | Viera | Florida | 32940 | — |
| Conquest Research, LLC | Winter Park | Florida | 32789 | — |
| CenExel iResearch, LLC | Decatur | Georgia | 30030 | — |
| Hawaii Pacific Neuroscience, LLC | Honolulu | Hawaii | 96817 | — |
| Josephson Wallack Munshower Neurology, P.C. | Indianapolis | Indiana | 46256 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Michigan State University (MSU)- Health Team- Neurology and Ophthalmology Clinic | East Lansing | Michigan | 48824-7037 | — |
| Quest Research Institue | Farmington Hills | Michigan | 48334 | — |
| Parkinson's Disease and Movement Disorders Center of Long Island | Commack | New York | 11725-3400 | — |
| Mount Sinai West (Mount Sinai Roosevelt) | New York | New York | 10019-1147 | — |
| Ohio State University Wexner Medical Center (OSUWMC) - CarePoint Gahanna | Columbus | Ohio | 43211 | — |
| The Movement Disorder Clinic (MDC) of Oklahoma | Tulsa | Oklahoma | 74136-6372 | — |
| Abington Neurology | Abington | Pennsylvania | 19001 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina (MUSC) - The Murray Center for Research on Parkinson's Disease and Related Disorders | Charleston | South Carolina | 29401-1189 | — |
| Veracity Neuroscience, LLC | Memphis | Tennessee | 38157 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| University of Virginia Health System (UVAHS)- Adult Neurology Clinic | Charlottesville | Virginia | 22903 | — |
| Inland Northwest Research | Spokane | Washington | 99202-1342 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05357989, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 2, 2025 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05357989 live on ClinicalTrials.gov.