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Completed Phase 2 Interventional Accepts healthy volunteers Results available

28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease

ClinicalTrials.gov ID: NCT05358821

Public ClinicalTrials.gov record NCT05358821. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 28-Day Randomized, Placebo-Controlled, Double-Blind, Parallel Groups and Normative Comparison Study to Evaluate the Effect of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease

Study identification

NCT ID
NCT05358821
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Supernus Pharmaceuticals, Inc.
Industry
Enrollment
69 participants

Conditions and interventions

Interventions

  • SAGE-718 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
25 Years to 65 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 25, 2022
Primary completion
Feb 28, 2024
Completion
Apr 9, 2024
Last update posted
Sep 14, 2025

2022 – 2024

United States locations

U.S. sites
13
U.S. states
12
U.S. cities
13
Facility City State ZIP Site status
Sage Investigational Site Birmingham Alabama 35233
Sage Investigational Site Los Alamitos California 90720
Sage Investigational Site Englewood Colorado 80113
Sage Investigational Site Washington D.C. District of Columbia 20057
Sage Investigational Site Boca Raton Florida 33431
Sage Investigational Site Tampa Florida 33602
Sage Investigational Site Chicago Illinois 60612
Sage Investigational Site Baltimore Maryland 21218
Sage Investigational Site New York New York 10027
Sage Investigational Site Chapel Hill North Carolina 27599
Sage Investigational Site Cincinnati Ohio 45221
Sage Investigational Site Philadelphia Pennsylvania 19104
Sage Investigational Site Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05358821, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 14, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05358821 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →