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Completed Phase 3 Interventional

A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome

ClinicalTrials.gov ID: NCT05358886

Public ClinicalTrials.gov record NCT05358886. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 12:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Parallel Group Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome

Study identification

NCT ID
NCT05358886
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Tetra Discovery Partners
Industry
Enrollment
171 participants

Conditions and interventions

Interventions

  • BPN14770/ zatolmilast Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2022
Primary completion
Jul 17, 2025
Completion
Jul 17, 2025
Last update posted
Jul 9, 2026

2022 – 2025

United States locations

U.S. sites
17
U.S. states
13
U.S. cities
17
Facility City State ZIP Site status
Amnova Clinical Research Irvine California 92604
Thompson Autism & Neurodevelopment Center - CHOC Orange California 92868
UC Davis Health System Sacramento California 95817
Children's Hospital Colorado Aurora Colorado 80045
University of Miami Miami Florida 33136
Emory University School of Medicine Atlanta Georgia 30322
Rush University Medical Center Chicago Illinois 60612
University of Kansas Medical Center Kansas City Kansas 66160
Kennedy Krieger Institute Baltimore Maryland 21205
Boston Children's Hospital Boston Massachusetts 02115
University of Massachusetts Medical School Worcester Massachusetts 01655
Icahn School of Medicine at Mount Sinai Hospital New York New York 10029
Cincinnati Childrens Hospital Medical Center Cincinnati Ohio 45229
Suburban Research Associates Media Pennsylvania 19063
Clinic for Special Children Strasburg Pennsylvania 17579
Greenwood Genetic Center Greenville South Carolina 29605
University of Utah and Primary Childrens Hospital Salt Lake City Utah 84113

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05358886, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 9, 2026 · Synced Jul 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05358886 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →