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Completed Phase 2 Interventional

Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

ClinicalTrials.gov ID: NCT05359861

Public ClinicalTrials.gov record NCT05359861. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 11:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase 2 Trial of Atezolizumab and Bevacizumab in Combination With SRF388 or Placebo in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma

Study identification

NCT ID
NCT05359861
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Coherus Oncology, Inc.
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

  • Atezolizumab Drug
  • Bevacizumab Drug
  • Placebo Drug
  • SRF388 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 11, 2022
Primary completion
Jun 29, 2025
Completion
Jul 7, 2025
Last update posted
Mar 17, 2026

2022 – 2025

United States locations

U.S. sites
15
U.S. states
9
U.S. cities
13
Facility City State ZIP Site status
University of Arizona Cancer Center - North Campus Tucson Arizona 85719
City of Hope Duarte California 91010
University of Southern California - Norris Comprehensive Cancer Center Los Angeles California 90033
University of Florida Health Science Center - Gainesville Gainesville Florida 32610
University of Miami, Sylvester Comprehensive Cancer Center Miami Florida 33136
Louisville VA Medical Center - Robley Rex VA Medical Center Louisville Kentucky 40206
Veterans Affairs Ann Arbor Healthcare System Ann Arbor Michigan 48105
University of Michigan Health System (UMHS) Ann Arbor Michigan 48109
Henry Ford Hospital Detroit Michigan 48202
Veterans Affairs New York Harbor Healthcare System - Manhattan VA Medical Center New York New York 10010
NYU Langone Medical Center - Laura and Isaac Perlmutter Cancer Center (NYU Cancer Institute (NYUCI)) New York New York 10016
University of Oklahoma Health Sciences Center - Stephenson Cancer Center Oklahoma City Oklahoma 73104
Providence Portland Medical Center Portland Oregon 97213
Sarah Cannon Research Institute - Tennessee Oncology Chattanooga Tennessee 37404
Sarah Cannon Research Institute - Tennessee Oncology Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05359861, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 17, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05359861 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →