Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
Public ClinicalTrials.gov record NCT05360446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase IIIb Study Evaluating the Effect of Inclisiran on Atherosclerotic Plaque Progression Assessed by Coronary Computed Tomography Angiography (CCTA) in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (VICTORION-PLAQUE)
Study identification
- NCT ID
- NCT05360446
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 610 participants
Conditions and interventions
Conditions
Interventions
- Inclisiran sodium 300 mg Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 7, 2022
- Primary completion
- Oct 25, 2026
- Completion
- Oct 25, 2026
- Last update posted
- Apr 13, 2026
2022 – 2026
United States locations
- U.S. sites
- 27
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research Llc | Huntsville | Alabama | 35801 | — |
| Alaska Heart and Vascular | Anchorage | Alaska | 99508 | — |
| Cardiovascular Res Found | Beverly Hills | California | 90210 | — |
| UC San Diego Health | La Jolla | California | 92037 | — |
| Stanford Health Care | Stanford | California | 94305 | — |
| Lundquist Inst BioMed at Harbor | Torrance | California | 90509-2910 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| George Washington Univ Medical Ctr | Washington D.C. | District of Columbia | 20037 | — |
| Inpatient Research Clinical LLC | Miami Lakes | Florida | 33014 | — |
| NorthShore University Health System | Evanston | Illinois | 60201 | — |
| Reid Physician Associates | Richmond | Indiana | 47374 | — |
| Midwest Heart and Vascular Spec | Overland Park | Kansas | 66211 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| R Ins For Heart And Vascular Health | Reno | Nevada | 89502 | — |
| Cardio Metabolic Institute | Somerset | New Jersey | 08873 | — |
| Icahn School of Med at Mt Sinai | New York | New York | 10029 | — |
| State Uni of NY at Stony Brook | Stony Brook | New York | 11794-3362 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Oregon Health Sciences University | Portland | Oregon | 97239 | — |
| Soltero Cardiovascular Research Center | Dallas | Texas | 75226 | — |
| Orion Medical | Houston | Texas | 77034 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Swedish Medical Center-Cardiovascular Research | Seattle | Washington | 98122 | — |
| Univ of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 62 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05360446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced May 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05360446 live on ClinicalTrials.gov.