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Completed Phase 2 Interventional

A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria

ClinicalTrials.gov ID: NCT05368285

Public ClinicalTrials.gov record NCT05368285. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 4:39 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Dose-finding Study to Assess the Efficacy and Safety of CDX-0159 in Patients With Chronic Spontaneous Urticaria

Study identification

NCT ID
NCT05368285
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Celldex Therapeutics
Industry
Enrollment
208 participants

Conditions and interventions

Interventions

  • Matching Placebo Drug
  • barzolvolimab Biological

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 18, 2022
Primary completion
Sep 27, 2023
Completion
Dec 19, 2024
Last update posted
Mar 25, 2025

2022 – 2024

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
Clinical Research Center of Alabama dba Allervie Clinical Research Birmingham Alabama 35249
Medical Research of Arizona Scottsdale Arizona 85251
Little Rock Allergy & Asthma CRC Little Rock Arkansas 72205
Kern Research, Inc Bakersfield California 93301
Allergy & Asthma Consultants Redwood City California 94063
IMMUNOe Research Centers Centennial Colorado 80112
Treasure Valley Medical Research Boise Idaho 83706
Allergy & Asthma Specialists, PSC Owensboro Kentucky 42301
Institute for Asthma and Allergy Chevy Chase Maryland 20815
Chesapeake Clinical Research White Marsh Maryland 21162
Respiratory Medicine Research Institute of Michigan, PLC Ypsilanti Michigan 48197
University of Nebraska Medical Center Omaha Nebraska 68198
Montefiore Medical Center/Subspeciality-Allergy and Immunology The Bronx New York 10461

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05368285, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 25, 2025 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05368285 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →